Risks and benefits related to alimentary exposure to xenoestrogens.
Risks and benefits related to alimentary exposure to xenoestrogens.
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DOI：
10.1080/10408398.2015.1126547
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发表时间：
2017-11-02
影响因子：
10.2
通讯作者：
Minutolo F
中科院分区：
文献类型：
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作者：
Paterni I;Granchi C;Minutolo F
异种雌激素在环境和食物中广泛扩散，因此全世界有很大一部分人口接触到它们。在食物性异雌激素中，植物雌激素 (PhyEs) 由于其潜在的健康益处而被越来越多地消耗，尽管其摄入也存在重大风险。此外，食物中可能存在的其他异雌激素是具有雌激素活性的其他化学物质，通常被定义为内分泌干扰化学物质（EDC）。 EDC 造成了严重的健康问题，因为它们可能会导致广泛的健康问题，从出生前到成人终生接触。我们在此概述了异种雌激素的主要类别，这些异种雌激素根据其来源、结构及其在食物链中的出现情况进行分类。此外，本综述还讨论了它们对人类健康的有益或毒性影响。
Xenoestrogens are widely diffused in the environment and in food, thus a large portions of human population is worldwide exposed to them. Among alimentary xenoestrogens, phytoestrogens (PhyEs) are increasingly being consumed because of their potential health benefits, although there are also important risks associated to their ingestion. Furthermore, other xenoestrogens that may be present in food are represented by other chemicals possessing estrogenic activities, that are commonly defined as endocrine disrupting chemicals (EDCs). EDCs pose a serious health concern since they may cause a wide range of health problems, starting from pre-birth till adult lifelong exposure. We herein provide an overview of the main classes of xenoestrogens, which are classified on the basis of their origin, their structures and their occurrence in the food chain. Furthermore, their either beneficial or toxic effects on human health are discussed in this review.
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