Effect of preterm birth on growth and blood pressure in adulthood in the Pelotas 1993 cohort.
Effect of preterm birth on growth and blood pressure in adulthood in the Pelotas 1993 cohort.
复制标题
DOI：
10.1093/ije/dyad084
复制
发表时间：
2023-12-25
影响因子：
7.7
通讯作者：
中科院分区：
文献类型：
--
作者：
早产与成年后高血压和心血管疾病的风险增加有关，这归因于生命早期的心血管和代谢改变。然而，来自低收入和中等收入国家的证据很少。我们采用线性回归法研究了1993年巴西骨盆出生队列中早产（胎龄<37周）和足月出生个体在出生身长和体重以及成年（18岁和20岁）身高、体重和血压方面的差异。分析调整了孕妇体重在怀孕开始和母亲的教育和家庭收入在分娩。其他模型根据体重指数（BMI）和出生体重进行了调整。对雄性和雌性进行单独分析。完整的样本进行了分析与性别的相互作用项。在出生时纳入的3585名婴儿中，有3010名在22岁时成年。早产儿参与者出生时身长和体重较低。男性参与者在成年后仍然存在这种差异，但女性参与者在18岁时并不比他们的长期同行短。22岁时，早产女性的血压（收缩压-1.00 mmHg，95%CI-2.7，0.7 mmHg;舒张压-1.1 mmHg，95%CI-2.4，0.3 mmHg）低于足月女性。在男性参与者中没有发现这些差异。在这个巴西队列中，我们发现了关于早产与年轻成年人血压相关性的对比结果，这可能是LMIC所独有的。
Preterm birth has been associated with increased risk of hypertension and cardiovascular disease later in adulthood, attributed to cardiovascular and metabolic alterations in early life. However, there is paucity of evidence from low- and middle-income countries (LMICs). We investigated the differences between preterm (<37 weeks gestational age) and term-born individuals in birth length and weight as well as adult (18 and 20 years) height, weight and blood pressure in the Brazilian 1993 Pelotas birth cohort using linear regressions. Analyses were adjusted for the maternal weight at the beginning of pregnancy and maternal education and family income at childbirth. Additional models were adjusted for body mass index (BMI) and birthweight. Separate analyses were run for males and females. The complete sample was analysed with an interaction term for sex. Of the 3585 babies included at birth, 3010 were followed up in adulthood at 22 years. Preterm participants had lower length and weight at birth. This difference remained for male participants in adulthood, but female participants were no shorter than their term counterparts by 18 years of age. At 22 years, females born preterm had lower blood pressures (systolic blood pressure −1.00 mmHg, 95%CI −2.7, 0.7 mmHg; diastolic blood pressure −1.1 mmHg, 95%CI −2.4, 0.3 mmHg) than females born at term. These differences were not found in male participants. In this Brazilian cohort we found contrasting results regarding the association of preterm birth with blood pressure in young adulthood, which may be unique to an LMIC.
登录
查看更多内容
影响因子：
8.3
作者：
Haikerwal, Anjali;Doyle, Lex W.;Cheong, Jeanie L. Y.
通讯作者：
Cheong, Jeanie L. Y.
影响因子：
8.2
作者：
Crump, Casey;Sundquist, Jan;Sundquist, Kristina
通讯作者：
Sundquist, Kristina
影响因子：
39.3
作者：
Crump, Casey;Sundquist, Jan;Sundquist, Kristina
通讯作者：
Sundquist, Kristina
影响因子：
82.9
作者：
Bernabe-Ortiz A;Sal Y Rosas VG;Ponce-Lucero V;Cárdenas MK;Carrillo-Larco RM;Diez-Canseco F;Pesantes MA;Sacksteder KA;Gilman RH;Miranda JJ
通讯作者：
Miranda JJ
影响因子：
8.3
作者：
Hovi, Petteri;Vohr, Betty;Kajantie, Eero
通讯作者：
Kajantie, Eero