Kin recognition and outer membrane exchange (OME) in myxobacteria.
Kin recognition and outer membrane exchange (OME) in myxobacteria.
复制标题
亲属识别和外膜交换(OME)。
DOI:
10.1016/j.mib.2020.07.003
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发表时间:
2020-08
影响因子:
5.4
通讯作者:
Wall D
中科院分区:
文献类型:
--
作者:
Sah GP;Wall D
Myxobacteria conduct complex social traits that requires populations to be highly related and devoid of exploiters. To enrich for clonal cells in populations, they employ kin discrimination mechanisms. One key system involves a polymorphic cell surface receptor, TraA, which recognizes self by homotypic interactions with neighboring myxobacterial cells. Recent studies revealed that TraA and its partner TraB are fluid outer membrane proteins that coalesce into foci upon recognition of kin. The formation of foci leads to transient membrane fusion junctions and the bidirectional exchange of outer membrane components that facilitates cooperative behaviors. Additionally, expansive suites of polymorphic lipoprotein toxins are exchanged, which act as self-identity barcodes that exquisitely discriminate against nonself to assemble homogenous populations.
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