Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2.

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2.
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COVID-19 中的内皮功能障碍需要立即关注:内皮在 SARS-CoV-2 引起的炎症中的新作用

DOI:
10.1007/s11684-021-0831-z
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发表时间:
2021-08
影响因子:
8.1
通讯作者:
Wang DW
Wang DW
中科院分区:
医学1区
文献类型:
--
作者:
Hang W;Chen C;Zhang XA;Wang DW

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COVID-19大流行在世界各地造成了大量死亡。越来越多的证据表明,压倒性炎症反应在COVID-19发病机制中的重要作用以及抗炎治疗对COVID-19的有效性正在显现。除了影响肺部外,COVID-19还可能是一种与内皮功能障碍有关的严重全身性炎症疾病。我们呼吁密切关注COVID-19内皮功能障碍,不仅可以充分揭示COVID-19的致病机制,还可以适当调整临床干预策略。
The COVID-19 pandemic has caused numerous deaths around the world. A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is emerging. In addition to affecting the lungs, COVID-19 can be a severe systemic inflammatory disease that is related to endothelial dysfunction. We are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing the pathogenic mechanism of COVID-19 but also for properly adjusting the strategy of clinical intervention.
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