Year-Round Respiratory Syncytial Virus Transmission in The Netherlands Following the COVID-19 Pandemic: A Prospective Nationwide Observational and Modeling Study.
Year-Round Respiratory Syncytial Virus Transmission in The Netherlands Following the COVID-19 Pandemic: A Prospective Nationwide Observational and Modeling Study.
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DOI：
10.1093/infdis/jiad282
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发表时间：
2023-11-11
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
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作者：
我们启动了一项全国性的前瞻性研究，以监测2021年5月至2022年8月期间荷兰46家医院的呼吸道合胞病毒（RSV）相关儿科住院情况。我们显示，在2021年夏季首次爆发后，荷兰全年都有RSV传播。这种模式是前所未有的，与邻国截然不同。我们扩展了一个动态模拟模型，以评估免疫力下降对荷兰儿科RSV住院治疗的影响，使用4种不同的方案。我们的研究结果表明，观察到的持续RSV传播模式可能与COVID-19大流行期间RSV循环非常低导致的免疫力下降有关。在一项全国性的前瞻性多中心研究中，我们显示了2019冠状病毒病大流行后荷兰非季节性疫情爆发后的全年呼吸道合胞病毒传播。我们扩展的动态模拟模型表明，这种新的连续传播模式可能与免疫力下降有关。
We initiated a nationwide prospective study to monitor respiratory syncytial virus (RSV)–related pediatric hospitalizations in 46 hospitals throughout the Netherlands between May 2021 and August 2022. We showed year-round RSV transmission in the Netherlands after an initial 2021 summer outbreak. The pattern was unprecedented and distinct from neighboring countries. We extended a dynamic simulation model to evaluate the impact of waning immunity on pediatric RSV hospitalizations in the Netherlands using 4 different scenarios. Our results suggest that the observed continuous RSV transmission pattern could be associated with waning immunity due to the period of very low RSV circulation during the COVID-19 pandemic. In a nationwide prospective multicenter study, we show year-round respiratory syncytial virus transmission after an out-of-season outbreak in the Netherlands following the COVID-19 pandemic. Our extended dynamic simulation model suggests that this novel continuous transmission pattern could be associated with waning immunity.
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影响因子：
56.3
作者：
Bardsley, Megan;Morbey, Roger A.;Hughes, Helen E.;Beck, Charles R.;Watson, Conall H.;Zhao, Hongxin;Ellis, Joanna;Smith, Gillian E.;Elliot, Alex J.
通讯作者：
Elliot, Alex J.
影响因子：
6.4
作者：
Reicherz, Frederic;Xu, Rui Yang;Lavoie, Pascal M.
通讯作者：
Lavoie, Pascal M.
DOI：
10.2807/1560-7917.es.2021.26.29.2100639
发表时间：
2021-07
期刊：
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
影响因子：
--
作者：
van Summeren J;Meijer A;Aspelund G;Casalegno JS;Erna G;Hoang U;Lina B;VRS study group in Lyon;de Lusignan S;Teirlinck AC;Thors V;Paget J
通讯作者：
Paget J
影响因子：
13.8
作者：
Zheng Z;Pitzer VE;Shapiro ED;Bont LJ;Weinberger DM
通讯作者：
Weinberger DM
影响因子：
56.3
作者：
Billard, Marie-Noelle;Bont, Louis J.
通讯作者：
Bont, Louis J.