Diverse roles of LPA signaling in the intestinal epithelium.
Diverse roles of LPA signaling in the intestinal epithelium.
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DOI:
10.1016/j.yexcr.2014.11.013
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发表时间:
2015-05-01
影响因子:
3.7
通讯作者:
Kumar, Ajay
中科院分区:
文献类型:
--
作者:
Yun, C. Chris;Kumar, Ajay
Lysophosphatidic acid (LPA) is a lipid mediator that modulates a wide variety of cellular functions. Elevated LPA signaling has been reported in patients with colorectal cancer or inflammatory bowel diseases, and the tumorigenic role of LPA has been demonstrated in experimental models of colon cancer. However, emerging evidence indicates the importance of LPA signaling in epithelial wound healing and regulation of intestinal electrolyte transport. Here, we briefly review current knowledge of the biological roles of LPA signalling in the intestinal tract.
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影响因子:
29.4
作者:
Lee SJ;Ritter SL;Zhang H;Shim H;Hall RA;Yun CC
通讯作者:
Yun CC
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He P;Yun CC
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Yun CC
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11.2
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Yang VW
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5.3
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Lee, Sei-Jung;Leoni, Giovanna;Yun, C. Chris
通讯作者:
Yun, C. Chris