Evidence of the interplay of genetics and culture in Ethiopia.
Evidence of the interplay of genetics and culture in Ethiopia.
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DOI：
10.1038/s41467-021-23712-w
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发表时间：
2021-06-11
影响因子：
16.6
通讯作者：
Hellenthal G
中科院分区：
文献类型：
--
作者：
López S;Tarekegn A;Band G;van Dorp L;Bird N;Morris S;Oljira T;Mekonnen E;Bekele E;Blench R;Thomas MG;Bradman N;Hellenthal G
埃塞俄比亚丰富的语言、种族和文化多样性为了解文化因素与人类群体遗传结构的相关程度和形状提供了前所未有的机会。使用主要是新的遗传变异数据，涵盖1,214个代表68个不同民族的埃塞俄比亚人，加上个人的出生地，语言/宗教习俗和31个文化习俗的信息，我们解开了地理距离，海拔和社会因素对今天埃塞俄比亚人遗传结构的影响。我们提供的证据表明，社会行为和遗传差异之间的联系，在当今的人民。我们发现，遗传相似性是广泛相关的语言联系，但也确定明显的遗传相似性组从不同的语言分类，可能部分是由于最近的混合。我们还说明了报告相同的文化特征的群体是如何平均遗传相似的，并显示出最近混合的证据，这表明共享的文化特征可能会促进混合。除了提供深入了解埃塞俄比亚的遗传结构和历史，我们确定了遗传分化的最重要的文化和地理预测因子，并为设计未来涉及埃塞俄比亚人的遗传研究的采样协议提供了资源。埃塞俄比亚是种族和文化最多样化的国家之一。在这里，作者研究了1,214名埃塞俄比亚人的遗传和文化变异，以揭示遗传混合物和文化因素之间的关系。
The rich linguistic, ethnic and cultural diversity of Ethiopia provides an unprecedented opportunity to understand the level to which cultural factors correlate with–and shape–genetic structure in human populations. Using primarily new genetic variation data covering 1,214 Ethiopians representing 68 different ethnic groups, together with information on individuals’ birthplaces, linguistic/religious practices and 31 cultural practices, we disentangle the effects of geographic distance, elevation, and social factors on the genetic structure of Ethiopians today. We provide evidence of associations between social behaviours and genetic differences among present-day peoples. We show that genetic similarity is broadly associated with linguistic affiliation, but also identify pronounced genetic similarity among groups from disparate language classifications that may in part be attributable to recent intermixing. We also illustrate how groups reporting the same culture traits are more genetically similar on average and show evidence of recent intermixing, suggesting that shared cultural traits may promote admixture. In addition to providing insights into the genetic structure and history of Ethiopia, we identify the most important cultural and geographic predictors of genetic differentiation and provide a resource for designing sampling protocols for future genetic studies involving Ethiopians. Ethiopia is one of the most ethnically and culturally diverse countries. Here, the authors look at genetic and cultural variation in 1,214 Ethiopians to unravel the relationship between genetic admixture and cultural factors.
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影响因子：
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作者：
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通讯作者：
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