Neural correlates of sensory preconditioning: A preliminary fMRI investigation

Neural correlates of sensory preconditioning: A preliminary fMRI investigation
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感觉预处理的神经相关性:初步功能磁共振成像研究

DOI:
10.1002/hbm.22253
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发表时间:
2013
影响因子:
4.8
通讯作者:
Kotchoubey
Kotchoubey
中科院分区:
医学2区
文献类型:
--
作者:
Birbaumer;Kotchoubey

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感觉预处理(SPC;也被称为行为沉默学习)由两种中性刺激的组合组成,其中没有一种刺激是无条件的反应。当其中一个刺激与无条件刺激(US)配对后,另一个中性刺激也会产生条件反应,尽管它从未与US配对。在这项研究中,事件相关的功能磁共振成像(fMRI)范式被用来指定涉及SPC的大脑区域。结果表明,SPC与几个区域的活动的显着变化,特别是,左侧杏仁核,左侧海马,双侧丘脑,双侧内侧苍白球,双侧小脑,双侧运动前皮质,双侧额中回。这是第一次尝试使用功能磁共振成像来检查SPC对大脑激活的影响。我们的数据表明,SPC中涉及包括皮层和皮层下区域的分布式结构网络,因此增加了我们对关联学习能力的神经机制的理解。© 2013威利期刊公司.
Sensory preconditioning (SPC; also known as behaviorally silent learning) consists of a combination of two neutral stimuli, none of which elicits an unconditional response. After one of them is later paired with an unconditional stimulus (US), the other neutral stimulus also yields a conditional response although it has never been paired with the US. In this study, an event‐related functional magnetic resonance imaging (fMRI) paradigm was used to specify brain regions involved in SPC. The results demonstrated that SPC was associated with significant changes in activity of several regions, notably, the left amygdala, the left hippocampus, the bilateral thalamus, the bilateral medial globus pallidus, the bilateral cerebellum, the bilateral premotor cortex, and the bilateral middle frontal gyrus. This is a first effort to use fMRI to examine the effects of SPC on brain activation. Our data suggest that there is a distributed network of structures involved in SPC including both cortical and subcortical regions, therefore add to our understanding of the neural mechanisms underlying the ability to associative learning.Hum Brain Mapp 35:1297–1304, 2014. © 2013 Wiley Periodicals, Inc.
DOI: 10.1016/s0166-4328(00)00168-6
发表时间: 2000-07-01
影响因子: 2.7
作者:
Nicholson, DA;Freeman, JH
通讯作者: Freeman, JH
DOI: 10.1523/jneurosci.1647-06.2006
发表时间: 2006-08-09
影响因子: 5.3
作者:
Dwyer, Dominic M.;Killcross, Simon
通讯作者: Killcross, Simon
DOI: --
发表时间: 2002
影响因子: 2.7
作者:
J. Ward;L. Wilton;J. Muir;R. C. Honey;S. Vann;J. Aggleton
通讯作者: J. Aggleton
感觉预处理的情境特异性:对事件内学习过程的影响
DOI: --
发表时间: 1998
期刊:
影响因子: --
作者:
J. Ward;M. Symonds;G. Hall
通讯作者: G. Hall
感觉预处理的回顾。
DOI: --
发表时间: 1959
影响因子: 22.4
作者:
R. Seidel
通讯作者: R. Seidel