Enhanced tissue differentiation in the developing mouse brain using magnetic resonance micro‐histology
Enhanced tissue differentiation in the developing mouse brain using magnetic resonance micro‐histology
复制标题
使用磁共振显微组织学增强发育中小鼠大脑的组织分化
DOI:
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发表时间:
2013
影响因子:
3.3
通讯作者:
M. Lythgoe
中科院分区:
文献类型:
--
作者:
F. Norris;J. Betts;J. Wells;J. Cleary;B. Siow;S. Walker;K. McCue;P. Salomoni;P. Scambler;M. Lythgoe
Purpose: Worldwide efforts to understand developmental processes demand new high‐resolution 3D imaging methods to detect the consequences of gene function in embryo development and diseases. Encouragingly, recent studies have shown that MRI contrast agents can highlight specific tissue structures in ex vivo adult mouse brains. MR imaging of mouse embryos is currently limited by a lack of tissue staining capabilities that would provide the flexibility and specificity offered by histological stains conventionally used for mouse embryo phenotyping.
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DOI:
10.1073/pnas.0403918101
发表时间:
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影响因子:
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