An Updated Review of Hypertrophic Scarring.
An Updated Review of Hypertrophic Scarring.
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作者:
Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with excessive deposition of extracellular matrix and connective tissue at the site of injury. In this review article, we provide an overview of normal (acute) wound healing phases (hemostasis, inflammation, proliferation, and remodeling). We next discuss the dysregulated and/or impaired mechanisms in wound healing phases that are associated with HTS development. We next discuss the animal models of HTS and their limitations, and review the current and emerging treatments of HTS.
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DOI:
10.2147/ccid.s50046
发表时间:
2014
期刊:
Clinical, cosmetic and investigational dermatology
影响因子:
--
作者:
Darby IA;Laverdet B;Bonté F;Desmoulière A
通讯作者:
Desmoulière A
影响因子:
4.8
作者:
Duncan, MR;Frazier, KS;Grotendorst, GR
通讯作者:
Grotendorst, GR
影响因子:
1.2
作者:
Delavary, Babak Mahdavian;Van der Veer, Willem M.;Niessen, Frank B.
通讯作者:
Niessen, Frank B.
影响因子:
4.8
作者:
Aarabi, Shahram;Bhatt, Kirit A.;Gurtner, Geoffrey C.
通讯作者:
Gurtner, Geoffrey C.
影响因子:
2.4
作者:
Abedini, Robabeh;Rayeni, Neda Mehdizade;Nasimi, Maryam
通讯作者:
Nasimi, Maryam