Body mass index can similarly predict the presence of multiple cardiovascular risk factors in middle-aged Japanese subjects as waist circumference.
Body mass index can similarly predict the presence of multiple cardiovascular risk factors in middle-aged Japanese subjects as waist circumference.
复制标题
体重指数与腰围类似，可以预测日本中年受试者是否存在多种心血管危险因素。
作者：
Hiroki Satoh;R. Kishi;H. Tsutsui
目标
肥胖与高血压、血脂异常和葡萄糖耐受不良等代谢危险因素的聚集密切相关。腰围和体重指数（BMI）分别是腹部肥胖和全身肥胖的既定标志。然而，尚未检验这两个标记是否可以检测日本受试者代谢危险因素的聚集。
方法和结果
我们研究了 5,796 名 40-60 岁的日本中年受试者（4,344 名男性和 1,452 名女性）。根据日本代谢综合征的诊断标准，确定了高血压、血脂异常和葡萄糖耐受不良等代谢危险因素。代谢危险因素的数量与男性和女性受试者的 BMI 值显着相关。男性和女性中具有多种（两种或两种以上）代谢危险因素的受试者患病率分别为 29.4% 和 7.6%。根据受试者工作特征（ROC）分析，BMI和腰围的曲线下面积在男性（0.658 vs. 0.671，p=n.s.）和女性（0.776 vs. 0.790，p=n.s.）受试者中没有差异，表明腰围和BMI可用于检测多种代谢危险因素的发生。男性和女性中预测多种代谢危险因素存在的 BMI 合适临界值分别为 24.7 和 23.4 kg/m(2)。使用这些临界值的敏感性和特异性在男性中分别为 58% 和 65%，在女性中分别为 65% 和 77%。
结论
BMI 值与日本中年受试者的腰围类似，可以预测多种代谢危险因素的存在。
OBJECTIVE
Adiposity is closely associated with the clustering of metabolic risk factors such as high blood pressure, dyslipidemia, and glucose intolerance. Waist circumference and body mass index (BMI) are the established markers of abdominal adiposity and general adiposity, respectively. However, it has not been examined whether these two markers can detect the clustering of metabolic risk factors in Japanese subjects.
METHODS AND RESULTS
We studied 5,796 Japanese middle-aged subjects aged 40-60 years (4,344 males and 1,452 females). Metabolic risk factors including high blood pressure, dyslipidemia, and glucose intolerance were identified according to the diagnostic criteria for metabolic syndrome in Japan. The number of metabolic risk factors was significantly associated with the BMI values in both male and female subjects. The prevalence of subjects with multiple (two or more) metabolic risk factors was 29.4% and 7.6% in males and females, respectively. According to receiver operating characteristic (ROC) analysis, the area under curve values of BMI and waist circumference did not differ in male (0.658 vs. 0.671, p=n.s.) and female (0.776 vs. 0.790, p=n.s.) subjects, indicating that the waist circumference as well as the BMI could be useful in detecting the occurrence of multiple metabolic risk factors. The appropriate cut-off values of BMI to predict the presence of multiple metabolic risk factors were 24.7 and 23.4 kg/m(2) in males and females, respectively. The sensitivity and specificity using these cut-off values were 58 and 65% in males and 65 and 77% in females, respectively.
CONCLUSION
The BMI values can similarly predict the presence of multiple metabolic risk factors just as the waist circumference in Japanese middle-aged subjects.
影响因子：
3.3
作者：
Shen, W;Punyanitya, M;Heshka, S
通讯作者：
Heshka, S
DOI：
10.1093/ajcn.81.2.409
发表时间：
2005-02
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Shankuan Zhu;S. Heymsfield;H. Toyoshima;Zimian Wang;A. Pietrobelli;S. Heshka
通讯作者：
Shankuan Zhu;S. Heymsfield;H. Toyoshima;Zimian Wang;A. Pietrobelli;S. Heshka