Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)--possible lessons from a systematic review of SARS-CoV therapy.
Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)--possible lessons from a systematic review of SARS-CoV therapy.
复制标题
DOI：
10.1016/j.ijid.2013.07.002
复制
发表时间：
2013-10
期刊：
影响因子：
--
通讯作者：
Al-Tawfiq JA
中科院分区：
文献类型：
--
作者：
Momattin H;Mohammed K;Zumla A;Memish ZA;Al-Tawfiq JA
中东呼吸综合征冠状病毒（MERS-CoV）已在中东和欧洲多个国家发现，死亡率明显较高。它在系统发育上与 SARS 冠状病毒相关，也与严重呼吸道疾病以及医疗机构中的医院传播有关。目前的国际建议不支持任何特定疗法；然而，有许多药物在 2003 年 SARS 流行期间使用过。这些药物可能对相关的 MERS 冠状病毒有活性。我们回顾了有关 SARS 患者治疗的安全性和有效性的文献，以期探讨它们在 MERS-CoV 感染患者中的潜在用途。
The Middle East Respiratory Syndrome coronavirus (MERS-CoV) has been detected in a number of countries in the Middle East and Europe with an apparently high mortality rate. It is phylogenetically related to the SARS coronavirus and has also been associated with severe respiratory illness as well as nosocomial transmission in healthcare settings. Current international recommendations do not support any specific therapies; however, there are a number of agents, which were used during the SARS epidemic of 2003. It is possible that these might be active against the related MERS coronavirus. We have reviewed the literature on the safety and efficacy of therapies used in patients with SARS with a view to their potential use in patients with MERS-CoV infections.
登录
查看更多内容
DOI：
10.1007/s10096-004-1271-9
发表时间：
2005-01
期刊：
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
影响因子：
--
作者：
Cheng Y;Wong R;Soo YO;Wong WS;Lee CK;Ng MH;Chan P;Wong KC;Leung CB;Cheng G
通讯作者：
Cheng G
影响因子：
3.3
作者：
Leong, HN;Ang, B;Leo, YS
通讯作者：
Leo, YS
影响因子：
15.8
作者：
Stockman LJ;Bellamy R;Garner P
通讯作者：
Garner P
影响因子：
10
作者：
Chu, CM;Cheng, VCC;Yuen, KY
通讯作者：
Yuen, KY
DOI：
10.1056/nejmoa1306742
发表时间：
2013-08-01
期刊：
The New England journal of medicine
影响因子：
--
作者：
Assiri A;McGeer A;Perl TM;Price CS;Al Rabeeah AA;Cummings DA;Alabdullatif ZN;Assad M;Almulhim A;Makhdoom H;Madani H;Alhakeem R;Al-Tawfiq JA;Cotten M;Watson SJ;Kellam P;Zumla AI;Memish ZA;KSA MERS-CoV Investigation Team
通讯作者：
KSA MERS-CoV Investigation Team