Ecological adaptation of diverse honey bee (Apis mellifera) populations.
Ecological adaptation of diverse honey bee (Apis mellifera) populations.
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DOI：
10.1371/journal.pone.0011096
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发表时间：
2010-06-15
期刊：
影响因子：
3.7
通讯作者：
Foster LJ
中科院分区：
文献类型：
--
作者：
Parker R;Melathopoulos AP;White R;Pernal SF;Guarna MM;Foster LJ
蜜蜂是一种复杂的社会性昆虫，对人类农业粮食生产做出了重要贡献。它们的自然迁徙选择了在地理区域内提高适合度的特征，但同时它们的驯化选择了提高当地条件下生产力和存活率的特征。阐明这些局部适应过程的生化机制是进化生物学的一个关键目标。蛋白质组学提供了在主要组学学科中独一无二的工具，用于确定有机体在适应环境挑战时所采用的机制。通过对地理上分散的驯化种群的成年蜜蜂中肠进行蛋白质组分析，结合多个平行的统计处理，这里提供的数据表明了一些涉及适应不同气候的主要细胞过程。这些发现提供了对可能赋予蜜蜂种群优势的分子基础的洞察。值得注意的是，在适应了较冷气候的蜜蜂中，线粒体的主要能量产生途径一直更高。线粒体是与产热最密切相关的细胞器。相反，从生物合成到降解，蛋白质代谢能力的上调被选择用于来自温暖气候的蜜蜂。总体而言，我们的结果提供了对蜜蜂生态型之间表达多态的蛋白质组学解释，并为蜜蜂局部适应或选择的分子方面提供了洞察，从而对蜜蜂管理和育种产生了影响。我们的研究结果的影响超越了养蜂业，因为它们强调了考虑动物种群及其农业生态环境相互依存的必要性。
Honey bees are complex eusocial insects that provide a critical contribution to human agricultural food production. Their natural migration has selected for traits that increase fitness within geographical areas, but in parallel their domestication has selected for traits that enhance productivity and survival under local conditions. Elucidating the biochemical mechanisms of these local adaptive processes is a key goal of evolutionary biology. Proteomics provides tools unique among the major ‘omics disciplines for identifying the mechanisms employed by an organism in adapting to environmental challenges. Through proteome profiling of adult honey bee midgut from geographically dispersed, domesticated populations combined with multiple parallel statistical treatments, the data presented here suggest some of the major cellular processes involved in adapting to different climates. These findings provide insight into the molecular underpinnings that may confer an advantage to honey bee populations. Significantly, the major energy-producing pathways of the mitochondria, the organelle most closely involved in heat production, were consistently higher in bees that had adapted to colder climates. In opposition, up-regulation of protein metabolism capacity, from biosynthesis to degradation, had been selected for in bees from warmer climates. Overall, our results present a proteomic interpretation of expression polymorphisms between honey bee ecotypes and provide insight into molecular aspects of local adaptation or selection with consequences for honey bee management and breeding. The implications of our findings extend beyond apiculture as they underscore the need to consider the interdependence of animal populations and their agro-ecological context.
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影响因子：
12.3
作者：
Fay JC;McCullough HL;Sniegowski PD;Eisen MB
通讯作者：
Eisen MB
蜜蜂转录组的表观遗传调控：揭示甲基化基因的本质。
影响因子：
4.4
作者：
Foret S;Kucharski R;Pittelkow Y;Lockett GA;Maleszka R
通讯作者：
Maleszka R
影响因子：
64.8
作者：
Alexopoulou, L;Holt, AC;Flavell, RA
通讯作者：
Flavell, RA
影响因子：
3.4
作者：
Boersema, Paul J.;Aye, Thin Thin;Mohammed, Shabaz
通讯作者：
Mohammed, Shabaz
影响因子：
2.4
作者：
Bouga, M;Kilias, G;Alahiotis, S
通讯作者：
Alahiotis, S