Do Quiescence and Wasp Venom-Induced Lethargy Share Common Neuronal Mechanisms in Cockroaches?
Do Quiescence and Wasp Venom-Induced Lethargy Share Common Neuronal Mechanisms in Cockroaches?
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DOI：
10.1371/journal.pone.0168032
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Libersat F
中科院分区：
文献类型：
--
作者：
Emanuel S;Libersat F
当蟑螂处于静止状态或被宝石黄蜂蜇伤后，蟑螂可能不会发生逃跑行为。在本文中，我们证明了静止是一种天生的昏睡状态，在此期间蟑螂对外部刺激的反应较弱。这种状态的神经元机制尚不清楚。与安静相反，毒液诱导的昏睡状态不是蟑螂的先天状态。宝石黄蜂通过将毒液直接注射到头神经节中来阻止蟑螂的逃跑行为。头神经节位于一个被称为中央复合体的神经堆中，是一个调节运动行为的“高级中枢”。在本文中，我们表明，与醒着的动物相比，静止动物的臀部慢运动神经元正在进行的活动减少，并且在被刺的动物中进一步减少。此外，在清醒和静止的蟑螂中都存在的慢运动神经元的有规律的强直性放电在被蜇的蟑螂中消失了。注射普鲁卡因来防止神经元活动进入中枢复合体，以模仿黄蜂毒液注射对慢运动神经元的活动产生类似的效果。综上所述，我们推测在静止和毒液诱导的昏睡状态中神经元的调节可能发生在中枢复合体中，并且这两种状态可能具有共同的神经元机制。
The escape behavior of a cockroach may not occur when it is either in a quiescent state or after being stung by the jewel wasp (Ampulex compressa). In the present paper, we show that quiescence is an innate lethargic state during which the cockroach is less responsive to external stimuli. The neuronal mechanism of such a state is poorly understood. In contrast to quiescence, the venom-induced lethargic state is not an innate state in cockroaches. The Jewel Wasp disables the escape behavior of cockroaches by injecting its venom directly in the head ganglia, inside a neuropile called the central complex a ‘higher center’ known to regulate motor behaviors. In this paper we show that the coxal slow motoneuron ongoing activity, known to be involved in posture, is reduced in quiescent animals, as compared to awake animals, and it is further reduced in stung animals. Moreover, the regular tonic firing of the slow motoneuron present in both awake and quiescent cockroaches is lost in stung cockroaches. Injection of procaine to prevent neuronal activity into the central complex to mimic the wasp venom injection produces a similar effect on the activity of the slow motoneuron. In conclusion, we speculate that the neuronal modulation during the quiescence and venom-induced lethargic states may occur in the central complex and that both states could share a common neuronal mechanism.
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影响因子：
2.8
作者：
Guo, Peiyuan;Ritzmann, Roy E.
通讯作者：
Ritzmann, Roy E.
DOI：
10.1007/s00359-005-0620-1
发表时间：
2005-06-01
影响因子：
2.1
作者：
Haspel, G;Gefen, E;Libersat, F
通讯作者：
Libersat, F
DOI：
10.1007/bf00612037
发表时间：
1986-01-01
影响因子：
2.1
作者：
RITZMANN, RE;POLLACK, AJ
通讯作者：
POLLACK, AJ
DOI：
10.1007/bf00199481
发表时间：
1994-11-01
期刊：
JOURNAL OF COMPARATIVE PHYSIOLOGY A-SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY
影响因子：
--
作者：
HOMBERG, U
通讯作者：
HOMBERG, U
影响因子：
2.9
作者：
MORALES, F;CHASE, MH
通讯作者：
CHASE, MH