Recent advances in radiotherapy treatment planning.

Recent advances in radiotherapy treatment planning.
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放射治疗计划的最新进展。

DOI:
--
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发表时间:
1991
影响因子:
2.4
通讯作者:
J. Tepper
J. Tepper
中科院分区:
医学4区
文献类型:
--
作者:
Eli Glatstein;J. Rosenman;Edward L. Chaney;S. Sailer;G. Sherouse;J. Tepper

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放射治疗计划目前正处于快速变化的状态。对过去计划技术的不满源于越来越多的人认识到:(1)局部区域肿瘤控制率的提高将提高许多恶性肿瘤的治愈率。(2)即使在最好的治疗中心,几何肿瘤错过是司空见惯的。(3)对治疗技术的传统限制,最初是为了简单和可重复性而施加的,现在已经没有必要了,而且可能导致次优治疗。(4)当在整个治疗体积上观察时,在两个维度上判断为“最佳”的治疗计划可能远非最佳。(5)缺乏治疗可重复性也是常见的,并且可以证明对治疗结果产生不利影响。从积极的方面来看,计算机图形学、图像处理、辐射物理学和辐射生物学的最新发展现在使定义、设计和提供复杂的3D辐射治疗成为可能。然而,由于这些技术中的许多技术正在为其他学科开发,因此它们对放射疗法治疗计划的适用性并没有得到广泛认可。我们概述了放射治疗计划的现状和新发展。
Radiation treatment planning is currently in a state of rapid change. Dissatisfaction with past planning technology stems from the growing realization that: (1) Increases in the local regional tumor control rate will increase the cure rate in many malignancies. (2) Even at the best treatment centers geometric tumor misses are commonplace. (3) Traditional constraints on treatment techniques, originally imposed for simplicity and reproducibility, are no longer necessary, and can result in suboptimal treatment. (4) Treatment plans judged "optimal" in two dimensions may be far from optimal when viewed over the entire treatment volume. (5) Lack of treatment reproducibility is also commonplace, and can be demonstrated to adversely affect treatment outcome. On the positive side, recent developments in computer graphics, image processing, radiation physics, and radiation biology are now making it possible to define, design, and deliver sophisticated 3D radiation treatments. However, because many of these technologies are being developed for other disciplines, their applicability to radiation therapy treatment planning is not widely appreciated. We outline the current status and new developments in radiation therapy treatment planning.
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发表时间: 1985
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影响因子: --
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DOI: --
发表时间: 1985
期刊: Radiation research. Supplement
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DOI: 10.1016/0360-3016(86)90083-0
发表时间: 1986
期刊: International journal of radiation oncology, biology, physics
影响因子: --
作者:
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通讯作者: Tepper,JE
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DOI: 10.1159/000413236
发表时间: 1987
影响因子: --
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通讯作者: Chen,GT