A 1.5T MRI-conditional 12-lead electrocardiogram for MRI and intra-MR intervention.

A 1.5T MRI-conditional 12-lead electrocardiogram for MRI and intra-MR intervention.
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DOI:
10.1002/mrm.24744
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发表时间:
2014-03
影响因子:
3.3
通讯作者:
Schmidt, Ehud J.
Schmidt, Ehud J.
中科院分区:
医学3区
文献类型:
--
作者:
Tse, Zion Tsz Ho;Dumoulin, Charles L.;Clifford, Gari D.;Schweitzer, Jeff;Qin, Lei;Oster, Julien;Jerosch-Herold, Michael;Kwong, Raymond Y.;Michaud, Gregory;Stevenson, William G.;Schmidt, Ehud J.

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高保真12导联心电图(ECG)对于MR引导介入和心脏MR成像期间的患者生理监测非常重要。在MRI内获得未损坏ECG的问题包括叠加磁流体动力学(MHD)电压、梯度切换感应电压和射频(RF)加热。这些问题随着磁场的增加而增加。我们打算开发和临床确认1.5T MRI特定条件安全12导联ECG系统。该系统的构建,包括传输线,以减少射频感应,和开关电路,以消除感应电压。自适应滤波器,训练的12导联测量MRI外和MRI内的两个方向,用于消除MHD。该系统进行了测试,10(一个行使)志愿者和4心律失常患者。开关电路消除了大部分成像感应电压(残留噪声<R波的3%)。去除MHD后,MRI内ECG与MRI外ECG的变化<3.8%,保留了真实的ST段。在室性早搏(PVC)患者中,干净的ECG将PVC和窦性心律搏动分开。测得的加热<1.5 C0。该系统可靠地采集了多相(SSFP)室壁运动电影和相位对比电影扫描,包括4导联门控失败的受试者。系统要求最小TR为4ms,以实现稳健的ECG处理。高保真MRI内12导联ECG是可能的。
High-fidelity 12-lead Electrocardiogram (ECG) is important for physiological monitoring of patients during MR-guided intervention and cardiac MR imaging. Issues in obtaining non-corrupted ECGs inside MRI include a superimposed Magneto-Hydro-Dynamic (MHD) voltage, gradient-switching induced-voltages, and radiofrequency (RF) heating. These problems increase with magnetic field. We intended to develop and clinically validate a 1.5T MRI-conditional 12-lead ECG system. The system was constructed, including transmission-lines to reduce radio-frequency induction, and switching-circuits to remove induced voltages. Adaptive filters, trained by 12-lead measurements outside MRI and in two orientations inside MRI, were used to remove MHD. The system was tested on ten (one exercising) volunteers and four arrhythmia patients. Switching circuits removed most imaging-induced voltages (residual noise <3% of the R-wave). MHD removal provided intra-MRI ECGs that varied by <3.8% from those outside the MRI, preserving the true ST segment. In premature-ventricular-contraction (PVC) patients, clean ECGs separated PVC and sinus-rhythm beats. Measured heating was <1.5 C0. The system reliably acquired multiphase (SSFP) wall-motion-cine and phase-contrast-cine scans, including in subjects where 4-lead gating failed. The system required a minimum TR of 4ms to allow robust ECG processing. High-fidelity intra-MRI 12-lead ECG is possible.
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