A 1.5T MRI-conditional 12-lead electrocardiogram for MRI and intra-MR intervention.
A 1.5T MRI-conditional 12-lead electrocardiogram for MRI and intra-MR intervention.
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DOI:
10.1002/mrm.24744
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发表时间:
2014-03
影响因子:
3.3
通讯作者:
Schmidt, Ehud J.
中科院分区:
文献类型:
--
作者:
Tse, Zion Tsz Ho;Dumoulin, Charles L.;Clifford, Gari D.;Schweitzer, Jeff;Qin, Lei;Oster, Julien;Jerosch-Herold, Michael;Kwong, Raymond Y.;Michaud, Gregory;Stevenson, William G.;Schmidt, Ehud J.
High-fidelity 12-lead Electrocardiogram (ECG) is important for physiological monitoring of patients during MR-guided intervention and cardiac MR imaging. Issues in obtaining non-corrupted ECGs inside MRI include a superimposed Magneto-Hydro-Dynamic (MHD) voltage, gradient-switching induced-voltages, and radiofrequency (RF) heating. These problems increase with magnetic field. We intended to develop and clinically validate a 1.5T MRI-conditional 12-lead ECG system. The system was constructed, including transmission-lines to reduce radio-frequency induction, and switching-circuits to remove induced voltages. Adaptive filters, trained by 12-lead measurements outside MRI and in two orientations inside MRI, were used to remove MHD. The system was tested on ten (one exercising) volunteers and four arrhythmia patients. Switching circuits removed most imaging-induced voltages (residual noise <3% of the R-wave). MHD removal provided intra-MRI ECGs that varied by <3.8% from those outside the MRI, preserving the true ST segment. In premature-ventricular-contraction (PVC) patients, clean ECGs separated PVC and sinus-rhythm beats. Measured heating was <1.5 C0. The system reliably acquired multiphase (SSFP) wall-motion-cine and phase-contrast-cine scans, including in subjects where 4-lead gating failed. The system required a minimum TR of 4ms to allow robust ECG processing. High-fidelity intra-MRI 12-lead ECG is possible.
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