Analysis of Liquid–Liquid Droplets Fission and Encapsulation in Single/Two Layer Microfluidic Devices Fabricated by Xurographic Method

Analysis of Liquid–Liquid Droplets Fission and Encapsulation in Single/Two Layer Microfluidic Devices Fabricated by Xurographic Method
复制标题

通过Xurography方法制造的单层/双层微流体装置中液体-液滴裂变和封装的分析

DOI:
10.3390/mi8020049
复制
发表时间:
2017-02-10
期刊:
影响因子:
3.4
通讯作者:
Yan Y
Yan Y
中科院分区:
工程技术3区
文献类型:
--
作者:
Lim CN;Koh KS;Ren Y;Chin JK;Shi Y;Yan Y

文献摘要

参考文献

被引文献

相似文献

本文介绍了一种用于微尺度液滴裂变和封装的低成本制造方法。利用改进的X光照相方法,开发了设计灵活的快速而可靠的微流控器件(单层和双层),以实现液滴操纵的空间控制。本文论证了两种不同的设计,即液滴分裂(单层)和液滴封装(双层)。此外,目前的制造方法通过引入定制的聚二甲基硅氧烷(PDMS)定向器来缩短总体生产间隔。此外,所制作的器件能够产生变异系数(CV)小于5%的子液滴和CV保持在10%以内的双乳状液,而不涉及复杂的表面润湿性改性。
This paper demonstrates a low cost fabrication approach for microscale droplet fission and encapsulation. Using a modified xurography method, rapid yet reliable microfluidic devices with flexible designs (single layer and double layer) are developed to enable spatial control of droplet manipulation. In this paper, two different designs are demonstrated, i.e., droplet fission (single layer) and droplet encapsulation (double layer). In addition, the current fabrication approach reduces the overall production interval with the introduction of a custom-made polydimethylsiloxane (PDMS) aligner. Apart from that, the fabricated device is able to generate daughter droplets with the coefficient of variance (CV) below 5% and double emulsions with CV maintained within 10% without involvement of complex surface wettability modification.
DOI: 10.1038/nprot.2013.046
发表时间: 2013-05
期刊: NATURE PROTOCOLS
影响因子: 14.8
作者:
Mazutis, Linas;Gilbert, John;Ung, W. Lloyd;Weitz, David A.;Griffiths, Andrew D.;Heyman, John A.
通讯作者: Heyman, John A.
DOI: 10.1023/a:1012448412811
发表时间: 2001-12-01
影响因子: 2.8
作者:
Weigl, Bernhard H.;Badrell, Ron;Hayenga, Jon
通讯作者: Hayenga, Jon
DOI: 10.1002/smll.200900569
发表时间: 2009-09-18
期刊: SMALL
影响因子: 13.3
作者:
Abate, A. R.;Weitz, D. A.
通讯作者: Weitz, D. A.
DOI: 10.1002/adma.201305119
发表时间: 2014-04-01
期刊: ADVANCED MATERIALS
影响因子: 29.4
作者:
Datta, Sujit S.;Abbaspourrad, Alireza;Weitz, David A.
通讯作者: Weitz, David A.
DOI: 10.1109/jmems.2005.859087
发表时间: 2005-12-01
影响因子: 2.7
作者:
Bartholomeusz, DA;Boutté, RW;Andrade, JD
通讯作者: Andrade, JD