Developing WHO rapid advice guidelines in the setting of a public health emergency.

Developing WHO rapid advice guidelines in the setting of a public health emergency.
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DOI:
10.1016/j.jclinepi.2016.08.010
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发表时间:
2017-03
影响因子:
7.2
通讯作者:
Moher D
Moher D
中科院分区:
医学2区
文献类型:
--
作者:
Garritty CM;Norris SL;Moher D

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我们描述了为世界卫生组织(世卫组织)指南制定人员新制定的关于在突发公共卫生事件(例如2014年埃博拉疫情)背景下制定快速咨询指南的过程和程序的指南。我们的方法基于已建立的快速审查方法,这些方法已纳入世卫组织现有指南制定过程。与世卫组织负责监督本组织应对紧急情况的工作人员(n = 6)深入讨论了与快速制定指南有关的问题,进一步提供了指南。我们讨论了考虑快速咨询指南是否合适和可行的标准,并概述了开发阶段中各种贡献者的角色。此外,我们描述了执行快速审查所涉及的方法和步骤,它比标准指导过程更灵活和迭代。一般而言,快速建议指南涉及较短的时间线、较窄的范围和使用简化的证据审查方法。在制定标准指南和快速建议指南之间存在重要的区别。然而,世卫组织指南的核心原则适用于快速咨询指南,包括尽量减少偏见、采用透明程序和使用明确方法。
We describe newly established guidance for guideline developers at the World Health Organization (WHO) on the process and procedures for developing a rapid advice guideline in the context of a public health emergency (e.g., the 2014 Ebola epidemic). We based our approach on established rapid review methods, which were incorporated into existing WHO guideline development processes. Guidance was further informed by in-depth discussions of issues related to rapid guideline development with WHO staff (n = 6), who oversee the Organization's response to emergencies. We discuss criteria for considering if a rapid advice guideline is appropriate and feasible and outline the roles of various contributors across the phases of development. Further, we describe the methods and steps involved in performing rapid reviews, which are more fluid and iterative than for a standard guideline process. In general, rapid advice guidelines involve a shorter timeline, narrower scope, and the use of abbreviated methods for the evidence review. Important differences exist between developing a standard guideline and a rapid advice guideline. However, the core principles for WHO guidelines apply to rapid advice guidelines including minimizing bias, applying transparent processes and the use of explicit methods.
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