Predictors of Plasma Fluoride Concentrations in Children and Adolescents.
Predictors of Plasma Fluoride Concentrations in Children and Adolescents.
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儿童和青少年血浆氟浓度的预测因子。
DOI：
10.3390/ijerph17249205
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发表时间：
2020-12-09
影响因子：
--
通讯作者：
Fleisch AF
中科院分区：
文献类型：
--
作者：
Carwile JL;Ahrens KA;Seshasayee SM;Lanphear B;Fleisch AF
尽管人们越来越关注氟化物对儿童的神经毒性，但人们对除城市水氟化外的氟化物暴露源知之甚少。我们的目的是描述美国儿童的人口统计学、饮用水特征、饮食和口腔健康行为与血浆氟浓度的关系。我们使用了来自2013-2016年全国健康和营养检查调查的3928名6-19岁儿童的数据。我们使用24小时饮食回忆来估计最近的氟化自来水和选择食物的消费量。我们评估了含氟自来水、最后一次牙科就诊时间、牙膏使用情况和每日刷牙频率与血浆氟浓度的关系。饮用含氟（≥0.7 mg/L）自来水的参与者（n = 560，16%）与未饮用含氟自来水的参与者相比，血浆氟高出36%（95% CI：22，51）。喝红茶或绿色茶的儿童（n = 503，13%）的血浆氟化物浓度比不喝茶的儿童高42%（95%CI：27，58）。其他食物的摄入和口腔卫生行为与血浆氟浓度无关。饮用含氟自来水和茶会显著增加儿童血浆氟浓度。量化饮食和其他氟化物来源的贡献对于建立城市水氟化的安全目标水平至关重要。
Despite increasing concerns about neurotoxicity of fluoride in children, sources of fluoride exposure apart from municipal water fluoridation are poorly understood. We aimed to describe the associations of demographics, drinking water characteristics, diet, and oral health behaviors with plasma fluoride concentrations in U.S. children. We used data from 3928 6–19-year-olds from the 2013–2016 National Health and Nutrition Examination Survey. We used a 24-h dietary recall to estimate recent consumption of fluoridated tap water and select foods. We estimated the associations of fluoridated tap water, time of last dental visit, use of toothpaste, and frequency of daily tooth brushing with plasma fluoride concentrations. The participants who consumed fluoridated (≥0.7 mg/L) tap water (n = 560, 16%) versus those who did not had 36% (95% CI: 22, 51) higher plasma fluoride. Children who drank black or green tea (n = 503, 13%) had 42% higher plasma fluoride concentrations (95% CI: 27, 58) than non-tea drinkers. The intake of other foods and oral health behaviors were not associated with plasma fluoride concentrations. The consumption of fluoridated tap water and tea substantially increases plasma fluoride concentrations in children. Quantifying the contribution of diet and other sources of fluoride is critical to establishing safe target levels for municipal water fluoridation.
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影响因子：
26.1
作者：
Green, Rivka;Lanphear, Bruce;Till, Christine
通讯作者：
Till, Christine
影响因子：
4.3
作者：
Cao, J;Zhao, Y;Liu, J
通讯作者：
Liu, J
DOI：
10.14219/jada.archive.2006.0261
发表时间：
2006-05-01
影响因子：
3.9
作者：
Franzman, Michael R.;Levy, Steven M.;Broffitt, Barbara
通讯作者：
Broffitt, Barbara
DOI：
10.1034/j.1600-0528.2002.00002.x
发表时间：
2002-10-01
影响因子：
2.3
作者：
Jackson, RD;Brizendine, EJ;Dunipace, AJ
通讯作者：
Dunipace, AJ
影响因子：
2.3
作者：
Levy, SM;Warren, JJ;Wefel, JS
通讯作者：
Wefel, JS