Extending the limited transfer window hypothesis to inter-organelle DNA migration.
Extending the limited transfer window hypothesis to inter-organelle DNA migration.
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DOI：
10.1093/gbe/evr068
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发表时间：
2011
影响因子：
3.3
通讯作者：
Smith DR
中科院分区：
文献类型：
--
作者：
Smith DR
线粒体基因组通常含有大量的质体DNA（ptDNA）衍生序列（MTPT）。有人认为，与每个细胞具有许多质体的物种（多质体的）相比，每个细胞只有一个质体的物种（单质体的）中ptDNA的室间转移大大减少。这一假说还没有被应用到DNA从质体到线粒体的运动中。通过分析不同的单和多质体类群的细胞器基因组，我表明，MTPTs仅限于线粒体基因组的物种，每个细胞有许多质体，是不存在的那些与一个质体每个细胞或单质体分生系统。此外，所探索的最膨胀的线粒体基因组具有最大的MTPT含量。这些数据，像以前的结果ptDNA衍生的序列在核基因组中，支持的假设，质体数量和非编码线粒体DNA（mtDNA）的扩张和收缩的力量影响MTPT丰度。我还表明，质体基因组中的线粒体DNA衍生序列（PTMTs）是depadenoate，无论每个细胞的线粒体数量和质体基因组的大小，这可能反映了质体中缺乏DNA摄取系统。
Mitochondrial genomes often contain large amounts of plastid DNA (ptDNA)-derived sequences (MTPTs). It has been suggested that the intercompartmental transfer of ptDNA is greatly reduced in species with only a single plastid per cell (monoplastidic) as compared with those with many plastids per cell (polyplastidic). This hypothesis has not been applied to the movement of DNA from plastids to mitochondria. By analyzing the organelle genomes from diverse mono- and polyplastidic taxa, I show that MTPTs are restricted to the mitochondrial genomes of species with many plastids per cell and are absent from those with one plastid per cell or with monoplastidic meristematic systems. Moreover, the most bloated mitochondrial genomes that were explored had the largest MTPT contents. These data, like previous results on ptDNA-derived sequences in nuclear genomes, support the hypothesis that plastid number and the forces governing the expansion and contraction of noncoding mitochondrial DNA (mtDNA) influence MTPT abundance. I also show that plastid genomes are depauperate in mtDNA-derived sequences (PTMTs), irrespective of the number of mitochondria per cell and plastid genome size, which may reflect the lack of a DNA uptake system in plastids.
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影响因子：
3.3
作者：
Smith DR
通讯作者：
Smith DR
影响因子：
10.7
作者：
Smith, David Roy;Lee, Robert W.
通讯作者：
Lee, Robert W.
影响因子：
10.7
作者：
Richly, E;Leister, D
通讯作者：
Leister, D
影响因子：
3
作者：
BROWN R C;LEMMON B E
通讯作者：
LEMMON B E
影响因子：
3.5
作者：
Koulintchenko, M;Temperley, RJ;Lightowlers, RN
通讯作者：
Lightowlers, RN