Descending projections to the auditory midbrain: evolutionary considerations.
Descending projections to the auditory midbrain: evolutionary considerations.
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DOI：
10.1007/s00359-022-01588-5
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发表时间：
2023-01
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影响因子：
--
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哺乳动物下丘（IC）由多个下行投射系统大量支配。除了来自听觉皮层（AC）的一个主要针对中耳部的非听觉部分的大投射外，还有来自皮层、杏仁核、后丘脑和中耳部臂的非听觉区域的特征较少的投射。相比之下，青蛙的听觉中脑，被称为半圆形环体，是一个大的听觉整合中心，也接受下行输入。但主要来自丘脑后部，而没有来自一个假定的皮层同源物：背侧皮层的投射。虽然下降投射与许多类型的行为有关，但对其功能的统一理解尚未出现。在这里，我们采用比较的方法来理解IC的各种自上而下的调制器，以深入了解它们的功能。我们确定的一个关键问题是，哺乳动物和两栖动物的丘脑顶投影是否同源，以及它们是否与进化上更多来自大脑皮层的新衍生投影相互作用。我们还考虑了这些下行通路的行为意义，因为无尾动物有能力在没有皮质-丘投影的情况下导航复杂的声学景观。最后，我们建议用实验方法来回答这些问题。
The mammalian inferior colliculus (IC) is massively innervated by multiple descending projection systems. In addition to a large projection from the auditory cortex (AC) primarily targeting the non-lemniscal portions of the IC, there are less well-characterized projections from non-auditory regions of the cortex, amygdala, posterior thalamus and the brachium of the IC. By comparison, the frog auditory midbrain, known as the torus semicircularis, is a large auditory integration center that also receives descending input, but primarily from the posterior thalamus and without a projection from a putative cortical homolog: the dorsal pallium. Although descending projections have been implicated in many types of behaviors, a unified understanding of their function has not yet emerged. Here, we take a comparative approach to understanding the various top-down modulators of the IC to gain insights into their functions. One key question that we identify is whether thalamotectal projections in mammals and amphibians are homologous and whether they interact with evolutionarily more newly-derived projections from the cerebral cortex. We also consider the behavioral significance of these descending pathways, given anurans’ ability to navigate complex acoustic landscapes without the benefit of a corticocollicular projection. Finally, we suggest experimental approaches to answer these questions.
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影响因子：
3.5
作者：
Ponnath A;Farris HE
通讯作者：
Farris HE
影响因子：
3.4
作者：
Esser, KH;Eiermann, A
通讯作者：
Eiermann, A
DOI：
10.1076/ejom.37.2.182.4753
发表时间：
1999-04-01
期刊：
EUROPEAN JOURNAL OF MORPHOLOGY
影响因子：
--
作者：
Endepols, H;Walkowiak, W
通讯作者：
Walkowiak, W
影响因子：
2.9
作者：
FENG, AS
通讯作者：
FENG, AS
影响因子：
25
作者：
Bajo VM;Nodal FR;Moore DR;King AJ
通讯作者：
King AJ