DIfferential Subsampling with Cartesian Ordering (DISCO): a high spatio-temporal resolution Dixon imaging sequence for multiphasic contrast enhanced abdominal imaging.
DIfferential Subsampling with Cartesian Ordering (DISCO): a high spatio-temporal resolution Dixon imaging sequence for multiphasic contrast enhanced abdominal imaging.
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DOI：
10.1002/jmri.23602
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发表时间：
2012-06
影响因子：
4.4
通讯作者：
Vasanawala, Shreyas S.
中科院分区：
文献类型：
--
作者：
Saranathan, Manojkumar;Rettmann, Dan W.;Hargreaves, Brian A.;Clarke, Sharon E.;Vasanawala, Shreyas S.
为了开发和评估一种用笛卡尔订购（迪斯科）进行腹部成像的多相对比增强的MRI方法，称为差分亚采样。
开发了三维密度的伪随机K-A-Space分割方案，并与基于Dixon的脂肪 - 水分离算法结合使用，以生成具有强大的脂肪抑制作用的高临时分辨率图像，并且在空间分辨率或IRB中没有损害批准和知情同意书，与迪斯科和常规临床3D SPGR-DIXON（LAVA FLEX）一起成像，连续11例转交给腹部MRI的患者。序列都使用脂肪抑制的质量，人工制品的严重程度以及整体图像质量作为评估文物的评估，记录了具有血管造影阶段和肝伪像的时间相的数量。
迪斯科和熔岩挠性图像之间的脂肪抑制，伪像的严重程度或整体图像质量没有显着差异（p> 0.05，Wilcoxon签名的等级测试）。 （平均阶段分别为2和3）。
迪斯科有效地捕获了腹部病理的快速动力学，例如具有高时空分辨率的高增强肝病变，通常以4-5秒的临时分辨率实现了1.1×1.1×1.5×3 mm的空间分辨率。
To develop and evaluate a multiphasic contrast-enhanced MRI method called DIfferential Sub-sampling with Cartesian Ordering (DISCO) for abdominal imaging. A three-dimensional, variable density pseudo-random k-space segmentation scheme was developed and combined with a Dixon-based fat-water separation algorithm to generate high temporal resolution images with robust fat suppression and without compromise in spatial resolution or coverage. With IRB approval and informed consent, 11 consecutive patients referred for abdominal MRI at 3T were imaged with both DISCO and a routine clinical 3D SPGR-Dixon (LAVA FLEX) sequence. All images were graded by two radiologists using quality of fat suppression, severity of artifacts, and overall image quality as scoring criteria. For assessment of arterial phase capture efficiency, the number of temporal phases with angiographic phase and hepatic arterial phase was recorded. There were no significant differences in quality of fat suppression, artifact severity or overall image quality between DISCO and LAVA FLEX images (p > 0.05, Wilcoxon signed rank test). The angiographic and arterial phases were captured in all 11 patients scanned using the DISCO acquisition (mean number of phases were 2 and 3 respectively). DISCO effectively captures the fast dynamics of abdominal pathology such as hyperenhancing hepatic lesions with a high spatio-temporal resolution. Typically, 1.1×1.5×3 mm spatial resolution over 60 slices was achieved with a temporal resolution of 4–5 seconds.
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