From fat fruit fly to human obesity.
From fat fruit fly to human obesity.
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DOI：
10.1016/j.physbeh.2014.01.017
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发表时间：
2014-09
影响因子：
2.9
通讯作者：
Moran TH
中科院分区：
文献类型：
--
作者：
Smith WW;Thomas J;Liu J;Li T;Moran TH
Obesity is a chronic metabolic disease that has become a global problem. Although a tremendous amount of effort has been spent to prevent and treat obesity, its etiology is still largely unknown and there are not yet sufficient strategies to control obesity. Recently, the fruit fly, Drosophila melanogaster, has become a useful model for studying metabolic homeostasis and obesity related disorders. The goal of this mini-review is to summarize the recent achievements of Drosophila models and to highlight the experimental protocols used in studying feeding behavior and energy homeostasis in the fly. The Drosophila models provide useful tools to understand obesity pathogenesis and to develop novel therapeutics.
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DOI：
10.1073/pnas.0702726104
发表时间：
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影响因子：
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