Dominance status predicts social fear transmission in laboratory rats.
Dominance status predicts social fear transmission in laboratory rats.
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DOI:
10.1007/s10071-016-1013-2
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发表时间:
2016-11
期刊:
影响因子:
2.7
通讯作者:
Monfils, Marie-H.
中科院分区:
文献类型:
--
作者:
Jones, Carolyn E.;Monfils, Marie-H.
Acquiring information about stimuli that predict danger, through either direct experience or inference from a social context, is crucial for individuals’ ability to generate appropriate behaviors in response to threats. Utilizing a modified demonstrator–observer paradigm (fear conditioning by proxy) that allows for free interaction between subjects, we show that social dominance hierarchy, and the interactive social behaviors of caged rats, is predictive of social fear transmission, with subordinate rats displaying increased fear responses after interacting with a fear-conditioned dominant rat during fear retrieval. Fear conditioning by proxy conserves some of the pathways necessary for direct fear learning (e.g., lateral amygdala) but is unique in that it requires regions necessary for emotional regulation (e.g., anterior cingulate cortex), making this paradigm an important tool for evaluating learning and behavior in the laboratory setting. The online version of this article (doi:10.1007/s10071-016-1013-2) contains supplementary material, which is available to authorized users.
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