Computerized Planning of Prostate Cryosurgery and Shape Considerations.
Computerized Planning of Prostate Cryosurgery and Shape Considerations.
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DOI：
10.1177/1533034617716041
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发表时间：
2017-12
影响因子：
2.8
通讯作者：
Rabin Y
中科院分区：
文献类型：
--
作者：
Joshi P;Sehrawat A;Rabin Y
目前的研究旨在探索各种前列腺形状之间的可能关系，以及创建基于计算机的冷冻手术计划的难度。这项研究工作是一项正在进行的研究的一部分，以开发计算手段，以改善冷冻手术的培训和教育。这项研究使用了一个计算机化的计划，最近开发的冷冻手术培训原型的关键组成部分。计划的质量是衡量的整体缺陷量，专有的概念，这是指内部的目标区域和过冷区域外部的过冷区域。这项研究的结果在数值上证实，整体缺陷量随着冷冻探针数量的增加而减少，无论前列腺的几何形状如何。然而，实现最小可能缺陷所需的冷冻探针的数量可能不切实际地高（<30）。本研究的结果还表明，最佳冷冻探针布局与对称前列腺几何形状的较小缺陷相关，并且独立地，对于更好地类似于球体的前列腺模型。此外，当尿道穿过前列腺模型的中心时，通常实现较小的缺陷。本研究建议创建一个冷冻探针凸船体的目的，初步规划，这是一个子域的形状类似于前列腺，但在一个减少的大小。参数研究表明，冷冻探针凸形船体从前列腺包膜在所有方向上收缩7至9 mm作为规划的准最佳初始条件，即，放置在冷冻探针凸形船体中的冷冻探针的预选数量产生有利的优化结果。冷冻探针凸形船体可以加速基于计算机的规划，同时在缺乏计算机手段的情况下也被采用作为传统冷冻外科培训的概念。
The current study aims to explore possible relationships between various prostate shapes and the difficulty in creating a computer-based plan for cryosurgery. This research effort is a part of an ongoing study to develop computational means in order to improve cryosurgery training and education. This study uses a computerized planner—a key building block of a recently developed prototype for cryosurgery training. The quality of planning is measured by the overall defect volume, a proprietary concept which refers to undercooled areas internal to the target region and overcooled areas external to it. Results of this study numerically confirm that the overall defect volume decreases with an increasing number of cryoprobes, regardless of the geometry of the prostate. However, the number of cryoprobes required to achieve the smallest possible defect may be unrealistically high (<30). Results of this study also demonstrate that the optimal cryoprobe layout is associated with a smaller defect for symmetric prostate geometries and, independently, for prostate models that better resemble a sphere. Furthermore, a smaller defect is typically achieved when the urethra passes through the center of the prostate model. This study proposes to create a cryoprobe convex hull for the purpose of initial planning, which is a subdomain similar in shape to the prostate but at a reduced size. Parametric studies indicate that a cryoprobe convex hull contracted by 7 to 9 mm in all directions from the prostate capsule serves as a quasi-optimal initial condition for planning, that is, a preselected number of cryoprobes placed in the cryoprobe convex hull yields favorable results for optimization. The cryoprobe convex hull could accelerate computer-based planning, while also being adopted as a concept for traditional cryosurgery training, when computerized means are absent.
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影响因子：
4.9
作者：
Furuhata T;Song I;Zhang H;Rabin Y;Shimada K
通讯作者：
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DOI：
10.1016/j.jvir.2013.01.493
发表时间：
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