What matters most: quantifying an epidemiology of consequence.

What matters most: quantifying an epidemiology of consequence.
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DOI:
10.1016/j.annepidem.2015.01.016
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发表时间:
2015-05
影响因子:
5.6
通讯作者:
Galea, Sandro
Galea, Sandro
中科院分区:
医学3区
文献类型:
--
作者:
Keyes, Katherine;Galea, Sandro

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风险因素流行病学对公共卫生的重大成功作出了贡献。然而,在本文中,我们认为,对风险因素流行病学的关注导致流行病学越来越关注暴露对结果的精确因果效应的估计,而忽略了对产生人口健康的更广泛因果结构的参与。为了进行结果流行病学研究,需要进行系统的努力,让我们的科学参与到批判性反思中,既要考虑我们能够在多大程度上、在什么条件或假设下评估因果关系,也要考虑对不断变化的人口健康真正最重要的是什么。这种方法改变了学科的优先级和价值,要求我们重新定位如何组织我们提出的问题和我们使用的方法,以及我们如何向新兴学者教授流行病学。
Risk factor epidemiology has contributed to substantial public health success. In this essay, we argue, however, that the focus on risk factor epidemiology has led epidemiology to ever increasing focus on the estimation of precise causal effects of exposures on an outcome at the expense of engagement with the broader causal architecture that produces population health. To conduct an epidemiology of consequence, a systematic effort is needed to engage our science in a critical reflection both about how well and under what conditions or assumptions we can assess causal effects and also on what will truly matter most for changing population health. Such an approach changes the priorities and values of the discipline and requires reorientation of how we structure the questions we ask and the methods we use, as well as how we teach epidemiology to our emerging scholars.
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