Pavlovian valuation systems in learning and decision making.
Pavlovian valuation systems in learning and decision making.
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DOI：
10.1016/j.conb.2012.06.004
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发表时间：
2012-12
影响因子：
5.7
通讯作者：
Phillips PE
中科院分区：
文献类型：
--
作者：
Clark JJ;Hollon NG;Phillips PE
Environmental stimuli guide value-based decision making, but can do so through cognitive representation of outcomes or through general-incentive properties attributed to the cues themselves. We assert that these differences are conferred through the use of alternative associative structures differing in computational intensity. Using this framework, we review scientific evidence to discern the neural substrates of these assumed separable processes. We suggest that the contribution of the mesolimbic dopamine system to Pavlovian valuation is restricted to an affective system that is only updated through experiential feedback of stimulus-outcome pairing, whereas the orbitofrontal cortex contributes to an alternative system capable of inferential reasoning. Finally we discuss the interactions and convergence of these systems and their implications for decision making and its pathology.
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