Trends in HIV infection in the First Affiliated Hospital of Harbin, China.
Trends in HIV infection in the First Affiliated Hospital of Harbin, China.
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哈尔滨市第一附属医院HIV感染趋势
DOI：
10.1186/s12879-014-0605-1
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发表时间：
2014-11-25
影响因子：
3.7
通讯作者：
Guan XR
中科院分区：
文献类型：
--
作者：
Xu HF;Zhou HZ;Jiang LX;Zhang N;Zhang X;Guan XR
中国大部分城市的主要医院都有能力进行艾滋病毒检测。然而，它不是所有患者的常规检测，因此，许多患者不知道他们的艾滋病毒状况。为了了解艾滋病病毒感染率和感染的相关因素，我们检测了血清，以确定艾滋病病毒的状态，并分析了与艾滋病病毒感染的相关因素。我们收集了2007年1月1日至2012年12月31日期间在哈尔滨医科大学附属第一医院就诊的348，151例患者的血液样本。用ELISA筛选血清。如果检测结果为阳性，我们进行了两次额外的ELISA：用初始试剂盒重复一次，用另一个试剂盒重复一次。如果两种ELISA试剂盒中的任何一种检测结果为阳性，则在哈尔滨市疾病预防控制中心进行蛋白质印迹。在本研究过程中，住院患者的HIV阳性率显著增加。艾滋病病毒感染的患者出现不同的性别，年龄，职业，婚姻状况，教育程度和感染途径。艾滋病毒在男子中的流行率高于妇女。80%以上的艾滋病毒阳性患者没有接受过高等教育（> 12年）。2007年至2012年，艾滋病毒阳性患者主要通过性传播感染。在性行为感染方面，近年来通过同性性接触感染艾滋病毒的比率迅速上升，从36.4%到65.1%不等。近年来，被诊断为艾滋病毒阳性的患者人数有所增加。在医院提供常规艾滋病毒检测是可行的，可以增加与艾滋病毒护理和治疗的联系。本文的在线版本（doi：10.1186/s12879 - 014 - 0605 - 1）包含补充材料，可供授权用户使用。
Major hospitals in most Chinese cities have the capability to perform HIV testing. However, it is not a routine test for all patients and, as a result, many patients are not aware of their HIV status. To understand the rate of HIV infection and the factors associated with infection, we tested serum to determine HIV status and analyzed factors associated with HIV infection. We collected blood samples from 348,151 patients who visited the First Affiliated Hospital of Harbin Medical University from 1 January 2007 to 31 December 2012. Serum was screened with an ELISA. If the test was positive, we conducted two additional ELISAs: a repeat with the initial kit and one with another kit. If there was a positive result with either of these two ELISA kits, western blotting was performed at Harbin Centers for Disease Control and Prevention. The HIV positivity rate of inpatients significantly increased during the course of this study. HIV infection in patients appeared to differ by sex, age, occupation, marital status, educational level, and route of infection. HIV was more prevalent in men than in women. More than 80% of HIV-positive patients had not received higher (>12 years) education. From 2007 to 2012, HIV-positive patients were mainly infected through sexual transmission. For sexually acquired infections, the rate of HIV infections through homosexual contact has increased rapidly in recent years, and ranged from 36.4% to 65.1%. The number of patients diagnosed as HIV positive has increased in recent years. Offering routine HIV testing in hospitals is feasible and can increase linkage to HIV care and treatment for many individuals. The online version of this article (doi:10.1186/s12879-014-0605-1) contains supplementary material, which is available to authorized users.
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作者：
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DOI：
10.4103/0253-7184.81247
发表时间：
2011-01
影响因子：
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DOI：
10.1097/qai.0b013e318211b41e
发表时间：
2011-05-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
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通讯作者：
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DOI：
10.1080/09540120903012528
发表时间：
2010-01-01
影响因子：
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通讯作者：
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