Evaluating the correlation between film mammography and MRI for screening women with increased breast cancer risk.
Evaluating the correlation between film mammography and MRI for screening women with increased breast cancer risk.
复制标题
DOI：
10.1016/j.acra.2009.05.011
复制
发表时间：
2009-11
影响因子：
4.8
通讯作者：
Gazelle, G. Scott
中科院分区：
文献类型：
--
作者：
Lee, Janie M.;Halpern, Elkan F.;Rafferty, Elizabeth A.;Gazelle, G. Scott
乳腺磁共振成像（MRI）越来越多地被添加到乳房X光检查中，用于筛查无症状的乳腺癌风险增加的妇女。由于乳腺X线摄影和MRI之间相关性的方向和程度可能导致高估或低估与使用MRI作为乳腺X线摄影筛查的辅助手段相关的诊断增益，因此我们进行了一项分析，以评价乳腺X线摄影和MRI之间的相关性程度。我们回顾了已发表的文献，以确定多模态乳腺癌筛查研究报告乳腺X线摄影和MRI的敏感性，单独和联合使用，乳腺癌诊断。在测试独立性（无相关性）条件下计算乳腺X线摄影和MRI组合的预期灵敏度后，我们比较了乳腺X线摄影和MRI组合的计算灵敏度和观察灵敏度。然后，我们计算了乳腺X线摄影和MRI的相关系数。纳入了7项在乳腺癌风险增加的女性中进行多模态筛查的研究进行分析。在这些研究中，3项研究中，胶片乳腺X线摄影和MRI之间的相关性为正，2项研究中为负，2项研究中未确定。计算的相关系数范围为-0.38至0.18。7项研究中有6项的相关系数的95%置信区间包括0.0，表明无显著相关性。来自已发表的多模态乳腺癌筛查试验的证据表明，胶片乳腺X线摄影和MRI之间无统计学显著相关性。使用这两种检测方法进行乳腺癌筛查可能会提高风险增加的女性乳腺癌的早期检测。
Breast magnetic resonance imaging (MRI) is increasingly being added to mammography for screening asymptomatic women at increased risk of breast cancer. Because the direction and extent of correlation between mammography and MRI could potentially result in over- or under-estimation of the diagnostic gain related to using MRI as an adjunct to mammographic screening, we performed an analysis to evaluate the extent of correlation between mammography and MRI. We reviewed the published literature to identify multimodality breast cancer screening studies reporting the sensitivity of mammography and MRI, alone and in combination, for breast cancer diagnosis. After calculating the expected sensitivity of combined mammography and MRI under conditions of test independence (no correlation), we compared the calculated and observed sensitivities for combined mammography and MRI. We then calculated correlation coefficients for mammography and MRI. Seven studies of multimodality screening in women at increased risk of developing breast cancer were included for analysis. Of these studies, the correlation between film mammography and MRI was positive in three studies, negative in two studies, and not identified in two studies. The calculated correlation coefficients ranged from -0.38 to 0.18. In 6 of 7 studies, the 95% confidence interval for the correlation coefficient included 0.0, indicating no significant correlation. Evidence from published trials of multimodality breast cancer screening identified no statistically significant correlation between film mammography and MRI. Using both tests for breast cancer screening is likely to improve the early detection of breast cancer in women at increased risk.
登录
查看更多内容
影响因子：
158.5
作者：
Meijers-Heijboer, H;van Geel, B;Klijn, JGM
通讯作者：
Klijn, JGM
DOI：
10.1111/j.1440-1673.2007.01907.x
发表时间：
2008-02-01
影响因子：
1.6
作者：
Peters, G.;Anderson, J.;Saunders, C.
通讯作者：
Saunders, C.
影响因子：
158.5
作者：
Kriege, M;Brekelmans, CTM;Klijn, JGM
通讯作者：
Klijn, JGM
影响因子：
1.9
作者：
Trecate, Giovanna;Vergnaghi, Daniele;Musumeci, Renato
通讯作者：
Musumeci, Renato
影响因子：
3.9
作者：
Hagen, Anne I.;Kvistad, Kjell Arne;Moller, Pal
通讯作者：
Moller, Pal