Dietary patterns associated with HbA1c and LDL cholesterol among individuals with type 1 diabetes in China.

Dietary patterns associated with HbA1c and LDL cholesterol among individuals with type 1 diabetes in China.
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DOI:
10.1016/j.jdiacomp.2014.12.014
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发表时间:
2015-04
影响因子:
3
通讯作者:
Mayer-Davis EJ
Mayer-Davis EJ
中科院分区:
医学3区
文献类型:
--
作者:
Jaacks LM;Crandell J;Mendez MA;Lamichhane AP;Liu W;Ji L;Du S;Rosamond W;Popkin BM;Mayer-Davis EJ

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确定影响中国1型糖尿病(T1 D)患者心脏代谢风险的饮食模式。数据来自中国T1 D的横断面研究(n=99)。通过三次24小时回忆来评估饮食摄入量。降秩回归被用来确定饮食模式,从一组20个食物组,最大限度地解释糖化血红蛋白A1 c(HbA 1c)和低密度脂蛋白(LDL)胆固醇的变化。膳食模式1的特点是小麦制品和高脂肪蛋糕的摄入量低,豆类和泡菜的摄入量高。膳食模式2的特点是低摄入量的高脂肪蛋糕,坚果/种子,鱼/贝类,茶/咖啡,和高摄入量的大米和鸡蛋。饮食模式1中最高三分位数的参与者与最低三分位数的参与者相比,HbA 1c和LDL胆固醇显着(p<0.05)更高:调整年龄和家庭收入后,HbA 1c的平均差异为1.0个百分点(11 mmol/mol),LDL胆固醇为0.36 mmol/L。饮食模式2与HbA 1c或LDL胆固醇无关。我们确定了一种与HbA 1c和LDL胆固醇显著相关的饮食模式。这些发现为中国T1 D患者预防并发症的行为策略提供了支持。
To identify dietary patterns that influence cardiometabolic risk among individuals with type 1 diabetes (T1D) in China. Data are from a cross-sectional study of T1D in China (n=99). Dietary intake was assessed using three 24-hour recalls. Reduced rank regression was used to identify dietary patterns from a set of 20 food groups that maximized the explained variation in glycated hemoglobin A1c (HbA1c) and low-density lipoprotein (LDL) cholesterol. Dietary pattern 1 was characterized by low intakes of wheat products and high-fat cakes, and high intakes of beans and pickled vegetables. Dietary pattern 2 was characterized by low intakes of high-fat cakes, nuts/seeds, fish/shellfish, and teas/coffee, and high intakes of rice and eggs. Participants in the highest tertile of dietary pattern 1 had significantly (p<0.05) higher HbA1c and LDL cholesterol compared to participants in the lowest tertile: mean difference in HbA1c was 1.0 percentage point (11mmol/mol) and in LDL cholesterol was 0.36 mmol/L after adjustment for age and household income. Dietary pattern 2 was not associated with HbA1c or LDL cholesterol. We identified a dietary pattern that is significantly related to HbA1c and LDL cholesterol. These findings provide support for behavioral strategies to prevent complications in individuals with T1D in China.
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