Dietary pattern trajectories during 15 years of follow-up and HbA1c, insulin resistance and diabetes prevalence among Chinese adults.
Dietary pattern trajectories during 15 years of follow-up and HbA1c, insulin resistance and diabetes prevalence among Chinese adults.
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DOI：
10.1136/jech-2013-203560
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发表时间：
2014-08
影响因子：
6.3
通讯作者：
Popkin B
中科院分区：
文献类型：
--
作者：
Batis C;Mendez MA;Sotres-Alvarez D;Gordon-Larsen P;Popkin B
大多数关于饮食模式和健康结果的研究不包括纵向暴露数据。我们使用一种创新的技术来捕捉饮食模式轨迹及其与血红蛋白A1c(HbA1c)、胰岛素抵抗的稳态模型(HOMA-IR)和新诊断的糖尿病患病率的关系。我们纳入了4,096名成年人，他们有三到六波的饮食数据(1991年至2006年)和2009年中国健康与营养调查中测量的生物标志物。通过三次24小时召回和一份家庭食品库存来评估饮食。我们使用了一种先前被确认为降级回归的饮食模式，该模式对2006年的糖尿病有积极的预测作用(高摄入小麦产品和豆奶，低摄入大米、豆类、家禽、鸡蛋和鱼)。我们为每个受试者在每一波中为这种饮食模式估计了一个分数。使用潜在班级轨迹分析，我们将饮食模式得分轨迹相似的受试者分成五个班级。三个轨迹类别随着时间的推移是稳定的，两个类别的饮食随着时间的推移变得更不健康(饮食模式得分有上升趋势)。在2006年得分相近的两个班级中，初始得分较低(较健康)的班级糖化血红蛋白降低1.64%(−1.64[95%可信区间=−3.17，−0.11])，HOMA-IR降低6.47%(−6.47[−17.37，4.42])，患糖尿病的几率较低(0.86[0.44，1.67])。我们的发现表明，与那些得分较低的饮食模式轨迹相比，纵向得分较健康的饮食模式轨迹的糖化血红蛋白较低，即使这些轨迹在终点的得分相似。
Most research on dietary patterns and health outcomes does not include longitudinal exposure data. We used an innovative technique to capture dietary pattern trajectories and their association with hemoglobin A1c (HbA1c), homeostasis model of insulin resistance (HOMA-IR), and prevalence of newly diagnosed diabetes. We included 4,096 adults with three to six waves of diet data (1991–2006) and biomarkers measured in 2009 from the China Health and Nutrition Survey. Diet was assessed with three 24-hour recalls and a household food inventory. We used a dietary pattern previously identified with reduced rank regression that positively predicted diabetes in 2006 (high in wheat products and soy milk and low in rice, legumes, poultry, eggs, and fish). We estimated a score for this dietary pattern for each subject at each wave. Using latent class trajectory analysis, we grouped subjects with similar dietary pattern score trajectories over time into five classes. Three trajectory classes were stable over time, and in two classes the diet became unhealthier over time (upward trend in dietary pattern score). Among two classes with similar scores in 2006, the one with the lower (healthier) initial score had an HbA1c 1.64% lower (−1.64 [95% confidence interval= −3.17, −0.11]) and nonsignificantly a HOMA-IR 6.47% lower (−6.47 [−17.37, 4.42]) and lower odds of diabetes (0.86 [0.44, 1.67]). Our findings suggest that dietary pattern trajectories with healthier scores longitudinally had a lower HbA1c compared to those with unhealthier scores, even when the trajectories had similar scores in the end point.
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影响因子：
3.6
作者：
Mikkilae, Vera;Rasnan, Leena;Viikari, Jorma
通讯作者：
Viikari, Jorma
影响因子：
4.7
作者：
Sargeant, LA;Khaw, KT;Wareham, NJ
通讯作者：
Wareham, NJ
影响因子：
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作者：
Fung, TT;Willett, WC;Hu, FB
通讯作者：
Hu, FB
影响因子：
16.2
作者：
Harding, AH;Sargeant, LA;Wareham, NJ
通讯作者：
Wareham, NJ
DOI：
10.1111/j.1751-9004.2007.00054.x
发表时间：
2008-01-01
影响因子：
4.6
作者：
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通讯作者：
Wickrama, K. A. S.