Coronary MRA: Technical Advances and Clinical Applications

Coronary MRA: Technical Advances and Clinical Applications
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冠状动脉 MRA:技术进步和临床应用

DOI:
10.1007/s12410-010-9064-2
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发表时间:
2011-01
影响因子:
0.9
通讯作者:
Qi Yang
Qi Yang
中科院分区:
--
文献类型:
--
作者:
Qi Yang

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磁共振血管成像(MRA)已成为评估头颈部、腹部和四肢动脉的常规临床工具。然而,冠状动脉MRA(CMRA)是一项更具挑战性的任务。许多因素阻碍了它的进展,包括:1)心脏在心跳和呼吸周期中的运动;2)非常曲折的过程;以及3)冠状动脉的细小。在确定CMRA成像参数时,必须在信噪比(SNR)、成像速度和空间分辨率之间取得适当的平衡。1.5T的全心CMRA已作为一种选择方法被成功引入,该方法可以在单个3D体积中提供所有三条主要冠状动脉的可视化。最近的单中心和多中心研究表明,1.5T全心CMRA可以在许多有冠状动脉疾病风险的患者中消除诊断冠状动脉插管的需要。3.0T心血管磁共振已成为近年来研究的热点。3.0T增强后的冠状动脉MRA可改善信噪比和对比噪声比,在检测显著的冠状动脉狭窄方面显示出很高的准确性。
Magnetic resonance angiography (MRA) has become a routine clinical tool to evaluate arteries in the head and neck, abdomen, and extremities. However, coronary MRA (CMRA) is a more challenging task. A number of factors have hindered its progress, including: 1) the motion of the heart during cardiac and respiratory cycles; 2) the highly tortuous courses; and 3) the small sizes of coronary arteries. It is important to have an appropriate balance between signal-to-noise ratio (SNR), imaging speed, and spatial resolution when determining imaging parameters of CMRA. Whole heart CMRA at 1.5 T has been successfully introduced as a method of choice that can provide visualization of all three major coronary arteries in a single 3D volume. Recent single and multicenter studies suggest that 1.5 T whole heart CMRA can eliminate the need for diagnostic coronary catheterization in many patients at risk of coronary artery disease. 3.0 T cardiovascular MR has become an area of active research in recent years. Contrast-enhanced coronary MRA at 3.0 T improves SNR and contrast-to-noise ratio and shows high accuracy in the detection of significant coronary artery stenoses.
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