Contrast-enhanced whole-heart coronary magnetic resonance angiography at 3.0-T: a comparative study with X-ray angiography in a single center.
Contrast-enhanced whole-heart coronary magnetic resonance angiography at 3.0-T: a comparative study with X-ray angiography in a single center.
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DOI：
10.1016/j.jacc.2009.03.016
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发表时间：
2009-06-30
影响因子：
24
通讯作者：
Li, Debiao
中科院分区：
文献类型：
--
作者：
Yang, Qi;Li, Kuncheng;Liu, Xin;Bi, Xiaoming;Liu, Zhi;An, Jing;Zhang, Al;Jerecic, Renate;Li, Debiao
本研究的目的是前瞻性评价3.0T增强全心冠状动脉磁共振血管成像(CMRA)对可疑冠心病患者的诊断价值。一种缓慢注入、对比剂增强的全心CMRA方法最近在3.0T下被开发出来。这种技术的准确性尚未在疑似冠状动脉疾病的患者中确定。连续69例患者行3.0T增强全心CMRA检查。采用心电触发、导航仪导航、倒置-恢复、分段梯度回波序列，缓慢注入0.2 mmol/kg Gd-BOPTA，获得各向同性全心CMRA。以X线血管造影术为参照，评价全心血管磁共振血管成像对显着狭窄(≥50%)的诊断准确性。62例患者顺利完成MR检查。全心CMRA手术获得时间为9.0±1.9min。3T全心CMRA正确诊断冠心病32例，排除冠心病23例。以每个节段为单位，全心CMRA诊断显著狭窄的敏感性、特异性和准确性分别为91.6%(87/95)、83.1%(570/686)、84.1%(657/781)。这些数值分别为94.1%(32/34)、82.1%(23/28)、88.7%(55/62)。3.0T增强全心CMRA可准确检测冠状动脉狭窄，灵敏度高，特异度适中。
The purpose of this study was to prospectively evaluate the diagnostic performance of 3.0T contrast-enhanced whole-heart coronary magnetic resonance angiography (CMRA) in patients with suspected coronary artery disease. A slow-infusion, contrast-enhanced whole-heart CMRA approach has recently been developed at 3.0T. The accuracy of such technique has not yet been determined among patients with suspected coronary artery disease. 3.0T contrast-enhanced whole-heart CMRA was performed in 69 consecutive patients. An ECG-triggered, navigator-gated, inversion-recovery prepared, segmented gradient-echo sequence was used to acquire isotropic whole-heart CMRA with slow infusion of 0.2 mmol/kg Gd-BOPTA. The diagnostic accuracy of whole-heart CMRA in detecting significant stenoses (≥50%) was evaluated using x-ray angiography as the reference. The MR examinations were successfully completed in 62 patients. Acquisition time of whole-heart CMRA procedure was 9.0 ±1.9 min. 3T whole-heart CMRA correctly identified significant CAD in 32 patients and correctly ruled out CAD in 23 patients. The sensitivity, specificity, and accuracy of whole-heart CMRA for detecting significant stenoses were 91.6% (87/95), 83.1% (570/686), 84.1% (657/781), respectively, on a per-segment basis. These values were 94.1% (32/34), 82.1% (23/28), 88.7% (55/62), respectively, on a per-patient basis. 3.0T contrast-enhanced whole-heart CMRA allows for the accurate detection of coronary artery stenosis with high sensitivity and moderate specificity.
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影响因子：
3.3
作者：
Nezafat, R;Stuber, M;Pettigrew, RI
通讯作者：
Pettigrew, RI
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24
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Haase, A
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作者：
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