Atypical attentional networks and the emergence of autism.

Atypical attentional networks and the emergence of autism.
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DOI:
10.1016/j.neubiorev.2012.11.014
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发表时间:
2013-02
影响因子:
8.2
通讯作者:
Townsend, Jeanne
Townsend, Jeanne
中科院分区:
医学1区
文献类型:
--
作者:
Keehn, Brandon;Mueller, Ralph-Axel;Townsend, Jeanne

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自闭症谱系障碍(ASD)的社会交际障碍在出生时并不存在,而是在生命的头两年逐渐出现。在典型的发展中,基本的注意过程可能为社会交际能力提供关键的基础。因此,早期注意力障碍的ASD可能会导致社会交往的非典型发展。先前的研究表明,ASD患者在注意力方面表现出早期和终身的障碍。本文的主要目的是提供一个审查现有的研究注意ASD使用的框架功能独立的注意网络概念化的Posner和同事:警觉,定向和执行控制网络。简要讨论了每种注意力网络的神经基质和典型发展,对ASD注意力文献进行了回顾,并提出了一个假设,将异常注意力机制(特别是注意力脱离受损)与核心ASD症状的出现联系起来。
The sociocommunicative impairments that define autism spectrum disorder (ASD) are not present at birth but emerge gradually over the first two years of life. In typical development, basic attentional processes may provide a critical foundation for sociocommunicative abilities. Therefore early attentional dysfunction in ASD may result in atypical development of social communication. Prior research has demonstrated that persons with ASD exhibit early and lifelong impairments in attention. The primary aim of this paper is to provide a review of the extant research on attention in ASD using a framework of functionally independent attentional networks as conceptualized by Posner and colleagues: the alerting, orienting and executive control networks. The neural substrates and typical development of each attentional network is briefly discussed, a review of the ASD attention literature is presented, and a hypothesis is proposed that links aberrant attentional mechanisms, specifically impaired disengagement of attention, with the emergence of core ASD symptoms.
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