Intrapulmonary distal airway stem cell transplantation repairs lung injury in chronic obstructive pulmonary disease.

Intrapulmonary distal airway stem cell transplantation repairs lung injury in chronic obstructive pulmonary disease.
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肺内远端气道干细胞移植修复慢性阻塞性肺疾病肺损伤

DOI:
10.1111/cpr.13046
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发表时间:
2021-06
期刊:
影响因子:
8.5
通讯作者:
Zuo W
Zuo W
中科院分区:
生物学1区
文献类型:
--
作者:
Wang X;Zhao Y;Li D;Feng Y;Xie Y;Zhou Y;Zhou M;Wang Y;Qu J;Zuo W

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慢性阻塞性肺疾病(COPD)的特征是不可逆的肺组织损伤,包括慢性支气管炎和肺气肿,可进一步发展为呼吸衰竭。许多研究表明,远端气道干/祖细胞(DASC)在肺损伤后具有潜在的再生功能。
Chronic obstructive pulmonary disease (COPD) is characterized by irreversible lung tissue damage including chronic bronchitis and emphysema, which could further develop into respiratory failure. Many studies have revealed a potential regenerative function of the distal airway stem/progenitor cells (DASCs) after lung injury.
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