Neuroimaging in the term newborn with neonatal encephalopathy.

Neuroimaging in the term newborn with neonatal encephalopathy.
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DOI:
10.1016/j.siny.2021.101304
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发表时间:
2021-10
影响因子:
3
通讯作者:
Chau, Vann
Chau, Vann
中科院分区:
医学3区
文献类型:
--
作者:
Wisnowski, Jessica L.;Wintermark, Pia;Bonifacio, Sonia L.;Smyser, Christopher D.;Barkovich, A. James;Edwards, A. David;de Vries, Linda S.;Inder, Terrie E.;Chau, Vann

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神经影像技术被广泛应用于新生儿脑病的诊断和临床治疗。然而,尽管在临床上广泛使用,但很少有发表的关于NE新生儿神经成像的指南。本文概述了NE新生儿缺氧缺血性脑损伤的主要类型、发生率、相关的神经病理学特征和危险因素。此外,它还提供了神经成像方法的概述,包括最广泛使用的评分系统,用于表征这些新生儿的脑损伤,以及它们作为预测性生物标志物的效用。最后,对NE新生儿的神经影像检查提出了建议。
Neuroimaging is widely used to aid in the diagnosis and clinical management of neonates with neonatal encephalopathy (NE). Yet, despite widespread use clinically, there are few published guidelines on neuroimaging for neonates with NE. This review outlines the primary patterns of brain injury associated with hypoxic-ischemic injury in neonates with NE and their frequency, associated neuropathological features, and risk factors. In addition, it provides an overview of neuroimaging methods, including the most widely used scoring systems used to characterize brain injury in these neonates and their utility as predictive biomarkers. Last, recommendations for neuroimaging in neonates with NE are presented.
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