Early experience and the development of stress reactivity and regulation in children.

Early experience and the development of stress reactivity and regulation in children.
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DOI:
10.1016/j.neubiorev.2009.05.007
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发表时间:
2010-05
影响因子:
8.2
通讯作者:
Early Experience, Stress, and Neurobehavioral Development Center
Early Experience, Stress, and Neurobehavioral Development Center
中科院分区:
医学1区
文献类型:
--
作者:
Loman MM;Gunnar MR;Early Experience, Stress, and Neurobehavioral Development Center

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在机构中度过早期生活的儿童或在其原籍家庭中受到虐待的儿童有可能出现情绪和行为问题,反映出情绪和注意力调节障碍。动物模型可能有助于解释产生这些效应的机制。尽管动物模型很有价值,但在使用动物数据指导人类发育研究方面仍存在许多问题。1999年,美国国家精神卫生研究所资助了一个研究网络,以解决尚未解决的问题,并加强将基本的动物早期经验研究转化为儿童研究的应用。西摩·莱文教授是这个研究网络的灵感来源和活跃成员,直到他于2007年10月去世。这篇评论通过概述现在指导我们研究的概念模型来向他的遗产致敬。
Children who spend early portions of their lives in institutions or those maltreated in their families of origin are at risk for developing emotional and behavioral problems reflecting disorders of emotion and attention regulation. Animal models may help explicate the mechanisms producing these effects. Despite the value of the animal models, many questions remain in using the animal data to guide studies of human development. In 1999, the National Institute of Mental Health in the United States funded a research network to address unresolved issues and enhance translation of basic animal early experience research to application in child research. Professor Seymour Levine was both the inspiration for and an active member of this research network until his death in October of 2007. This review pays tribute to his legacy by outlining the conceptual model which is now guiding our research studies.
DOI: 10.1007/s11121-008-0115-8
发表时间: 2009-06
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影响因子: 3.5
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