Interventions for Childhood Obesity in the First 1,000 Days A Systematic Review.

Interventions for Childhood Obesity in the First 1,000 Days A Systematic Review.
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DOI:
10.1016/j.amepre.2015.11.010
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发表时间:
2016-06
影响因子:
5.5
通讯作者:
Taveras EM
Taveras EM
中科院分区:
医学2区
文献类型:
--
作者:
Blake-Lamb TL;Locks LM;Perkins ME;Woo Baidal JA;Cheng ER;Taveras EM

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“最初的1,000天”--从受孕到24个月--对于儿童肥胖的发展和预防至关重要。本研究系统地审查了这一时期现有和正在进行的干预措施,确定了目前研究的差距,并讨论了未来干预措施的概念框架和机会。检索PubMed、Embase、Web of Science和Clinicaltrials.gov,以确定在怀孕至24个月期间实施的已完成和正在进行的干预措施,旨在预防6个月至18岁之间的超重/肥胖。对1980年1月1日至2014年12月12日期间发表的英语对照干预措施进行了分析,分析时间为2014年12月13日至2015年3月15日。在26项独特的干预措施的34项已完成研究中,9项有效。有效的干预措施侧重于个人或家庭层面的行为变化,通过家访,个人咨询或小组会议在临床环境中,家庭和小组访问相结合的社区设置,并使用水解蛋白质配方。富含蛋白质的配方奶增加儿童肥胖风险。确定了47项正在进行的干预措施。在已完成和正在进行的干预措施中,大多数针对个人或家庭层面的变化,许多是在临床环境中进行的,很少针对可能影响儿童肥胖的早期生活系统和政策。如果在生命早期开始,肥胖干预可能具有最大的预防效果。然而,在最初的1,000天里,几乎没有有效的干预措施,许多针对父母和婴儿的个人行为。在系统层面运作并以突出的概念框架为基础的干预措施有望改善未来的早期肥胖预防模式。
The “first 1,000 days”—conception through age 24 months—are critical for the development and prevention of childhood obesity. This study systematically reviews existing and ongoing interventions during this period, identifies gaps in current research, and discusses conceptual frameworks and opportunities for future interventions. PubMed, Embase, Web of Science, and Clinicaltrials.gov were searched to identify completed and ongoing interventions implemented during pregnancy through age 24 months that aimed to prevent overweight/obesity between age 6 months and 18 years. English-language, controlled interventions published between January 1, 1980, and December 12, 2014, were analyzed between December 13, 2014, and March 15, 2015. Of 34 completed studies from 26 unique identified interventions, nine were effective. Effective interventions focused on individual- or family-level behavior changes through home visits, individual counseling or group sessions in clinical settings, a combination of home and group visits in a community setting, and using hydrolyzed-protein formula. Protein-enriched formula increased childhood obesity risk. Forty-seven ongoing interventions were identified. Across completed and ongoing interventions, the majority target individual- or family-level changes, many are conducted in clinical settings, and few target early-life systems and policies that may impact childhood obesity. Obesity interventions may have the greatest preventive effect if begun early in life. Yet, few effective interventions in the first 1,000 days exist and many target individual-level behaviors of parents and infants. Interventions that operate at systems levels and are grounded in salient conceptual frameworks hold promise for improving future models of early-life obesity prevention.
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