Totopotensamides, polyketide-cyclic peptide hybrids from a mollusk-associated bacterium Streptomyces sp.
Totopotensamides, polyketide-cyclic peptide hybrids from a mollusk-associated bacterium Streptomyces sp.
复制标题
DOI:
10.1021/np200886x
复制
发表时间:
2012-04-27
影响因子:
5.1
通讯作者:
Schmidt EW
中科院分区:
文献类型:
--
作者:
Lin Z;Flores M;Forteza I;Henriksen NM;Concepcion GP;Rosenberg G;Haygood MG;Olivera BM;Light AR;Cheatham TE 3rd;Schmidt EW
Two new compounds, peptide-polyketide glycoside totopotensamide A (1) and its aglycone totopotensamide B (2), were isolated from Streptomyces sp. cultivated from the gastropod mollusk, Lienardia totopotens collected in the Philippines. The compounds contain a previously undescribed polyketide component, a novel 2,3-diaminobutyric acid-containing macrolactam, and a new amino acid, 4-chloro-5,7-dihydroxy-6-methylphenylglycine. The application of Marfey’s method to phenylglycine derivatives was explored using quantum mechanical calculations and NMR.
登录
查看更多内容
影响因子:
15
作者:
Sims, James W.;Schmidt, Eric W.
通讯作者:
Schmidt, Eric W.
影响因子:
5.1
作者:
Lin, Zhenjian;Antemano, Rowena R.;Schmidt, Eric W.
通讯作者:
Schmidt, Eric W.
影响因子:
7.4
作者:
Fujii, K;Ikai, Y;Harada, K
通讯作者:
Harada, K
影响因子:
4.4
作者:
Peraud, Olivier;Biggs, Jason S.;Schmidt, Eric W.
通讯作者:
Schmidt, Eric W.
DOI:
10.1635/053.161.0108
发表时间:
2011-10-01
影响因子:
0.7
作者:
Rosenberg, Gary
通讯作者:
Rosenberg, Gary