Dynamic task-specific brain network connectivity in children with severe reading difficulties.
Dynamic task-specific brain network connectivity in children with severe reading difficulties.
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DOI：
10.1016/j.neulet.2010.11.013
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发表时间：
2011-01-20
影响因子：
2.5
通讯作者：
Papanicolaou AC
中科院分区：
文献类型：
--
作者：
Vourkas M;Micheloyannis S;Simos PG;Rezaie R;Fletcher JM;Cirino PT;Papanicolaou AC
我们研究了阅读困难儿童（RD）和无阅读障碍儿童（NI）在假词阅读和字母-声音命名任务中的传感器水平功能连接模式，这些数据来自单试验全脑磁图数据。利用相位滞后指数（PLI），对每对传感器进行线性和非线性估计，根据图论构造图，得到局部和全局网络效率的估计。在8 ~ 13 Hz （alpha波段）和20 ~ 30 Hz （gamma波段）范围内，RD学生在整个脑磁图记录时期的整体效率明显低于NI儿童。RD学生在alpha波段也表现出局域网络效率的降低。语音解码能力和图形度量之间的相关性在对语音解码提出重大要求的任务中尤为明显，并且根据信号频率遵循不同的时间过程。结果与任务依赖的概念一致，自闭症儿童的远程和短程功能连接异常。
We investigated patterns of sensor-level functional connectivity derived from single-trial whole-head magnetoencephalography data during a pseudoword reading and a letter-sound naming task in children with reading difficulties (RD) and children with no reading impairments (NI). The Phase Lag Index (PLI), a linear and nonlinear estimator, computed for each pair of sensors, was used to construct graphs and obtain estimates of local and global network efficiency according to graph theory. In the 8 to 13 Hz (alpha band) and 20–30 Hz (gamma band) range, RD students showed significantly lower global efficiency than NI children, for the entire MEG recording epoch. RD students also displayed reduced local network efficiency in the alpha band. Correlations between phonological decoding ability and graph metrics were particularly evident during the task that posed significant demands for phonological decoding, and followed distinct time courses depending on signal frequency. Results are consistent with the notion of task-dependent, aberrant long- and short-range functional connectivity in RD children.
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影响因子：
2.6
作者：
Steinbrink, C.;Vogt, K.;Riecker, A.
通讯作者：
Riecker, A.
影响因子：
8.2
作者：
Pugh, KR;Mencl, WE;Gore, JC
通讯作者：
Gore, JC
影响因子：
5.7
作者：
Beaulieu, C;Plewes, C;Phillips, L
通讯作者：
Phillips, L
影响因子：
2.4
作者：
Simos, Panagiotis G.;Fletcher, Jack M.;Papanicolaou, Andrew C.
通讯作者：
Papanicolaou, Andrew C.
DOI：
10.1186/1753-4631-1-3
发表时间：
2007-07-05
期刊：
Nonlinear biomedical physics
影响因子：
--
作者：
Stam, Cornelis J;Reijneveld, Jaap C
通讯作者：
Reijneveld, Jaap C