Degradation dynamics, residues and risk assessment of Dufulin enantiomers in corn plants and corn by LC/MS/MS
Degradation dynamics, residues and risk assessment of Dufulin enantiomers in corn plants and corn by LC/MS/MS
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LC/MS/MS 玉米植株和玉米中杜芙灵对映体的降解动态、残留及风险评估
DOI：
10.1080/03601234.2018.1480165
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
De Y Hu
中科院分区：
文献类型：
--
作者：
Li H Shi;Shan Zhao;Ting Gui;Jin Xu;Fei Wang;Yu P Zhang;De Y Hu
摘要：研究了杜富林对映体在两种典型玉米植株中的降解动态和末端残留。开发并验证了一种方便、精确的手性方法，采用高效液相色谱与串联三重四极杆质谱 (HPLC/MS/MS) 结合使用 Chiralpak IC 柱来测量玉米植物和玉米中的杜富林对映体。杜富林的两种对映体在玉米植株中迅速消散，在降解过程中或最终残留物中没有观察到明显的立体选择性。 30%rac-都氟林可湿性粉剂按推荐剂量的1～1.5倍喷洒玉米植株2～3次后，最后一次施药后第7、14和21天，两地玉米中S-(+)-杜氟林和R-(-)-杜氟林残留水平均低于或等于0.0520 mg·kg–1。膳食风险评估表明，在实施良好农业规范的情况下，杜富林在玉米样品中并未表现出明显的膳食健康风险。这项研究的结果可用于更好地了解杜芙林在环境中的手性特征以及玉米中杜芙林残留对健康的影响。
ABSTRACT The degradation dynamics and terminal residues of dufulin enantiomers were investigated in two typical corn plants. A convenient and precise chiral method by high-performance liquid chromatography coupled with tandem triple quadrupole mass spectrometry (HPLC/MS/MS) using a Chiralpak IC column was developed and validated for measuring dufulin enantiomers in corn plants and corn. The two enantiomers of dufulin quickly dissipated in the corn plant, and no noticeable stereoselectivity was observed during degradation or in the final residues. After 30% rac-dufulin wettable powder with a 1- to 1.5-fold dose of the recommended value was sprayed two to three times on corn plants, the residue levels of S-(+)-dufulin and R-(-)-dufulin in corn from both sites were lower than or equal to 0.0520 mg kg–1 on days 7, 14 and 21 after the last application. The dietary risk assessment indicated that dufulin did not exhibit obvious dietary health risks in corn samples when good agricultural practices were implemented. The findings from this study may be used to better understand the chiral profiles of dufulin in the environment and the effect of dufulin residues in corn on health.
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影响因子：
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作者：
Zhang K;Hu D;Zhu H;Yang J;Wu J;He M;Jin L;Yang S;Song B
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DOI：
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Journal of Biology, Agriculture and Healthcare
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影响因子：
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DOI：
10.1080/03601230902801000
发表时间：
2009-01-01
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