Cell adhesion and signal transduction: the Armadillo connection.
Cell adhesion and signal transduction: the Armadillo connection.
复制标题
细胞粘附和信号转导:犰狳连接。
DOI:
10.1016/s0962-8924(00)89015-7
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发表时间:
1995
影响因子:
19
通讯作者:
M. Peifer
中科院分区:
文献类型:
--
作者:
M. Peifer
The products of the Drosophila segment polarity gene armadillo and its vertebrate homologue β-catenin are components of the signal transduction pathway for Wingless/Wnt-1; this signal regulates cell-fate choices in embryos of the fruit fly Drosophila and vertebrates. Armadillo/β-catenin is also a component of cell-cell adherens junctions in epithelia. How can these two seemingly distinct roles be reconciled? Evidence suggests that Armadillo has distinct functions: one in the adherens junction and one or more in the cytoplasm. The biochemical role of Armadillo may be to serve as a scaffold upon which different multiprotein complexes are assembled.
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影响因子:
4
作者:
Peifer,M
通讯作者:
Peifer,M
影响因子:
10.5
作者:
RIGGLEMAN, B;WIESCHAUS, E;SCHEDL, P
通讯作者:
SCHEDL, P
影响因子:
4.6
作者:
M. Peifer;D. Sweeton;Michael Casey;Eric Wieschaus
通讯作者:
M. Peifer;D. Sweeton;Michael Casey;Eric Wieschaus
影响因子:
56.9
作者:
MCCREA, PD;TURCK, CW;GUMBINER, B
通讯作者:
GUMBINER, B
DOI:
10.1242/dev.121.3.755
发表时间:
1995
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Pierce,SB;Kimelman,D
通讯作者:
Kimelman,D