A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012.
A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012.
复制标题
DOI：
10.1001/jamainternmed.2016.6807
复制
发表时间：
2017-01-01
影响因子：
39
通讯作者：
Weir, David R.
中科院分区：
文献类型：
--
作者：
Langa, Kenneth M.;Larson, Eric B.;Crimmins, Eileen M.;Faul, Jessica D.;Levine, Deborah A.;Kabeto, Mohammed U.;Weir, David R.
美国人口老龄化预计将导致成年痴呆症人数大幅增加，但美国和其他高收入国家最近的一些研究表明，在过去25年里，特定年龄段患痴呆症的风险可能有所下降。阐明痴呆症患病率和风险的当前和未来人口趋势对患者、家庭和政府项目具有重要意义。比较美国2000年和2012年的痴呆症患病率。我们使用了健康和退休研究(HRS)的数据，这是一项具有全国代表性的基于人口的美国成年人纵向调查。以人口为基础的美国成年人的预期队列。2000年(N=10,546)和2012年(N=10,511)HRS浪潮中65岁或以上的个人。每年使用HRS认知测量和有效的方法对自我受访者以及由代理人代表的人进行分类，以确定痴呆症。Logistic回归用于确定与2000至2012年间痴呆症患病率变化相关的社会经济和健康变量。65岁及以上人群的痴呆症患病率从2000年的11.6%降至2012年的8.8%(按年龄和性别标准化后为8.6%)(P<；0.001)。受教育年限越长，患痴呆症的风险越低，2000年至2012年间，平均受教育年限显著增加(从11.8年增加到12.7年；P<；0.001)。尽管经年龄和性别调整后，美国老年人的心血管风险状况(例如高血压、糖尿病和肥胖症的患病率)在多年之间显著增加，但痴呆症患病率仍在下降。2000年至2012年间，美国的痴呆症患病率大幅下降。教育程度的提高与痴呆症患病率的部分下降有关，但导致痴呆症患病率下降的全部社会、行为和医学因素仍不确定。随着未来几十年老年人数量的增加，继续监测痴呆症发病率和患病率的趋势对于更好地衡量痴呆症未来的全面社会影响将是重要的。
The aging of the US population is expected to lead to a large increase in the number of adults with dementia, but some recent studies in the US and other high-income countries suggest that the age-specific risk of dementia may have declined over the last 25 years. Clarifying current and future population trends in dementia prevalence and risk has important implications for patients, families, and government programs. To compare the prevalence of dementia in the United States in 2000 and 2012. We used data from the Health and Retirement Study (HRS), a nationally representative population-based longitudinal survey of US adults. Population-based prospective cohort of US adults. Individuals aged 65 or older from the 2000 (N = 10,546) and 2012 (N = 10,511) waves of the HRS. Dementia was identified in each year using HRS cognitive measures and validated methods for classifying self-respondents, as well as those represented by a proxy. Logistic regression was used to identify socioeconomic and health variables associated with change in dementia prevalence between 2000 and 2012. Dementia prevalence among those aged 65 or older decreased from 11.6% in 2000 to 8.8% (8.6% with age- and sex-standardization) in 2012 (P < 0.001). More years of education was associated with a lower risk for dementia, and average years of education increased significantly (from 11.8 to 12.7 years; P < 0.001) between 2000 and 2012. The decline in dementia prevalence occurred even though there was a significant age- and sex-adjusted increase between years in the cardiovascular risk profile (e.g., prevalence of hypertension, diabetes, and obesity) among older US adults. The prevalence of dementia in the United States declined significantly between 2000 and 2012. An increase in educational attainment was associated with some of the decline in dementia prevalence, but the full set of social, behavioral, and medical factors contributing to the decline is still uncertain. Continued monitoring of trends in dementia incidence and prevalence will be important for better gauging the full future societal impact of dementia as the number of older adults increases in the decades ahead.
登录
查看更多内容
影响因子：
168.9
作者：
Matthews, Fiona E.;Arthur, Antony;Barnes, Linda E.;Bond, John;Jagger, Carol;Robinson, Louise;Brayne, Carol
通讯作者：
Brayne, Carol
DOI：
10.1001/jama.2014.732
发表时间：
2014-02-26
期刊：
JAMA
影响因子：
--
作者：
Ogden CL;Carroll MD;Kit BK;Flegal KM
通讯作者：
Flegal KM
影响因子：
64.8
作者：
Deary, Ian J.;Yang, Jian;Visscher, Peter M.
通讯作者：
Visscher, Peter M.
影响因子：
14
作者：
Langa, Kenneth M.;Larson, Eric B.;Rosen, Allison B.
通讯作者：
Rosen, Allison B.
影响因子：
5.7
作者：
Langa, KM;Plassman, BL;Willis, RJ
通讯作者：
Willis, RJ