T1-/T2-weighted ratio reveals no alterations to gray matter myelination in temporal lobe epilepsy.
T1-/T2-weighted ratio reveals no alterations to gray matter myelination in temporal lobe epilepsy.
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DOI:
10.1002/acn3.51653
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发表时间:
2023-11
影响因子:
5.3
通讯作者:
Struck, Aaron F.
中科院分区:
文献类型:
--
作者:
Denis, Colin;Dabbs, Kevin;Nair, Veena A.;Mathis, Jedidiah;Almane, Dace N.;Lakshmanan, Akshayaa;Nencka, Andrew;Birn, Rasmus M.;Conant, Lisa;Humphries, Colin;Felton, Elizabeth;Raghavan, Manoj;Deyoe, Edgar A.;Binder, Jeffrey R.;Hermann, Bruce;Prabhakaran, Vivek;Bendlin, Barbara B.;Meyerand, Mary E.;Boly, Melanie;Struck, Aaron F.
Short‐range functional connectivity in the limbic network is increased in patients with temporal lobe epilepsy (TLE), and recent studies have shown that cortical myelin content correlates with fMRI connectivity. We thus hypothesized that myelin may increase progressively in the epileptic network. We compared T1w/T2w gray matter myelin maps between TLE patients and age‐matched controls and assessed relationships between myelin and aging. While both TLE patients and healthy controls exhibited increased T1w/T2w intensity with age, we found no evidence for significant group‐level aberrations in overall myelin content or myelin changes through time in TLE.
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DOI:
10.1523/jneurosci.2180-11.2011
发表时间:
2011-08-10
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Glasser MF;Van Essen DC
通讯作者:
Van Essen DC
影响因子:
9.9
作者:
Lee HW;Arora J;Papademetris X;Tokoglu F;Negishi M;Scheinost D;Farooque P;Blumenfeld H;Spencer DD;Constable RT
通讯作者:
Constable RT
影响因子:
5.6
作者:
Cole, AJ
通讯作者:
Cole, AJ
影响因子:
7.7
作者:
Mancini M;Karakuzu A;Cohen-Adad J;Cercignani M;Nichols TE;Stikov N
通讯作者:
Stikov N
影响因子:
5.6
作者:
Lariviere, Sara;Weng, Yifei;Bernhardt, Boris C.
通讯作者:
Bernhardt, Boris C.