Three 15-min bouts of moderate postmeal walking significantly improves 24-h glycemic control in older people at risk for impaired glucose tolerance.

Three 15-min bouts of moderate postmeal walking significantly improves 24-h glycemic control in older people at risk for impaired glucose tolerance.
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DOI:
10.2337/dc13-0084
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发表时间:
2013-10
期刊:
影响因子:
16.2
通讯作者:
Rumpler W
Rumpler W
中科院分区:
医学1区
文献类型:
--
作者:
DiPietro L;Gribok A;Stevens MS;Hamm LF;Rumpler W

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本研究的目的是比较 3 次 15 分钟饭后步行与 45 分钟持续步行对有葡萄糖不耐症风险的老年人 24 小时血糖控制的效果。不活跃的老年(≥60 岁)参与者 (N = 10) 是从社区招募的,不吸烟,BMI <35 kg/m2,空腹血糖浓度在 105 至 125 mg dL−1 之间。参与者完成了三个随机排序的锻炼方案,间隔 4 周。每个方案都包括在全房间热量计中停留 48 小时,第一天作为对照日。第二天,参与者进行 1) 餐后步行 15 分钟或 2) 上午 10:30 或 3) 下午 4:30 持续步行 45 分钟。所有行走均在跑步机上进行,绝对强度为 3 MET。使用连续血糖监测仪测定 48 小时内的间质葡萄糖浓度。通过呼吸交换(VCO2/VO2)连续测量底物利用率。与对照组相比,持续晨间步行(127±23 vs. 118±14 mg dL−1)和餐后步行(129±24 vs. 116±13 mg dL−1)均显着改善了 24 小时血糖控制(P < 0.05)。此外,在对照日和实验日之间,餐后步行在降低餐后 3 小时血糖方面比早上或下午持续步行 45 分钟显着更有效(P < 0.01)。短暂、间歇性的餐后步行似乎是控制老年人餐后高血糖的有效方法。
The purpose of this study was to compare the effectiveness of three 15-min bouts of postmeal walking with 45 min of sustained walking on 24-h glycemic control in older persons at risk for glucose intolerance. Inactive older (≥60 years of age) participants (N = 10) were recruited from the community and were nonsmoking, with a BMI <35 kg/m2 and a fasting blood glucose concentration between 105 and 125 mg dL−1. Participants completed three randomly ordered exercise protocols spaced 4 weeks apart. Each protocol comprised a 48-h stay in a whole-room calorimeter, with the first day serving as the control day. On the second day, participants engaged in either 1) postmeal walking for 15 min or 45 min of sustained walking performed at 2) 10:30 a.m. or 3) 4:30 p.m. All walking was on a treadmill at an absolute intensity of 3 METs. Interstitial glucose concentrations were determined over 48 h with a continuous glucose monitor. Substrate utilization was measured continuously by respiratory exchange (VCO2/VO2). Both sustained morning walking (127 ± 23 vs. 118 ± 14 mg dL−1) and postmeal walking (129 ± 24 vs. 116 ± 13 mg dL−1) significantly improved 24-h glycemic control relative to the control day (P < 0.05). Moreover, postmeal walking was significantly (P < 0.01) more effective than 45 min of sustained morning or afternoon walking in lowering 3-h postdinner glucose between the control and experimental day. Short, intermittent bouts of postmeal walking appear to be an effective way to control postprandial hyperglycemia in older people.
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