Urine heme dipsticks are useful in monitoring the impact of praziquantel treatment on Schistosoma haematobium in sentinel communities of Delta State, Nigeria.
Urine heme dipsticks are useful in monitoring the impact of praziquantel treatment on Schistosoma haematobium in sentinel communities of Delta State, Nigeria.
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DOI：
10.1016/j.actatropica.2012.01.002
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发表时间：
2012-04
期刊：
影响因子：
2.7
通讯作者：
Richards, Frank O.
中科院分区：
文献类型：
--
作者：
Emukah, Emmanuel;Gutman, Julie;Eguagie, John;Miri, Emmanuel S.;Yinkore, Paul;Okocha, Ndudi;Jibunor, Victoria;Nebe, Obiageli;Nwoye, Augustine Ikenna;Richards, Frank O.
尼日利亚是埃及血吸虫感染的高度流行地区，最常见的表现是尿液带血。监测吡喹酮年度集体给药（MDA）对沙门氏菌的影响。在尼日利亚三角洲州的一个调查中，在基线（n=240）和两次年度剂量（n =402）后，在8个哨点村庄（SV）对学童进行了横断面血尿调查。我们评估了三种血尿评估方法（儿童报告病史、护士目测诊断（NVD）和试纸法）的可比性，以确定是否需要进行大规模治疗。试纸被认为是黄金标准。治疗前，病史和NVD仅识别出3种最常见的SV，总体上仅占需要治疗的8种SV的37.5%。治疗后，试纸检测后患病率下降了88.5%（p<0.001），病史和NVD确定两个村庄中只有一个仍然需要治疗。这项研究表明，试纸应该是推荐的方法，启动和监测大规模治疗的S。埃及血吸虫
Nigeria is highly endemic for infection with Schistosoma haematobium, which most commonly manifests itself with blood in urine. To monitor the impact of annual mass drug administration (MDA) with praziquantel for S. haematobium in Delta State, Nigeria, cross-sectional hematuria surveys of school children were conducted in 8 sentinel villages (SVs) at baseline (n=240) and after two annual doses (n=402). We assessed the comparability of three assessments of hematuria (child’s reported history, nurse visual diagnosis (NVD) and dipstick) to determine the need for mass treatment. Dipstick was considered to be the gold standard. Prior to treatment, history and NVD each identified only the 3 most highly prevalent SVs, and overall this represented just 37.5% of the 8 SVs in need of treatment. Following treatment, after dipstick prevalence decreased by 88.5% (p<0.001), and history and NVD identified only one of two villages still needing treatment. The study suggests that dipsticks should be the recommended method for launching and monitoring mass treatment for S. haematobium.
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DOI：
10.1016/s0035-9203(96)90506-4
发表时间：
1996-07-01
影响因子：
2.2
作者：
Husein, MH;Talaat, M;Evans, DB
通讯作者：
Evans, DB
影响因子：
--
作者：
Gutman, J.;Fagbemi, A.;Richards, F. O., Jr.
通讯作者：
Richards, F. O., Jr.
DOI：
10.1016/0035-9203(82)90204-8
发表时间：
1982-01-01
影响因子：
2.2
作者：
FELDMEIER, H;DOEHRING, E;DAFFALLA, AA
通讯作者：
DAFFALLA, AA
影响因子：
2.7
作者：
Stothard, J. Russell;Sousa-Figueiredo, Jose C.;Rollinson, David
通讯作者：
Rollinson, David
影响因子：
3.8
作者：
Hotez PJ;Kamath A
通讯作者：
Kamath A