Prevalence of Physical Frailty and Its Multidimensional Risk Factors in Korean Community-Dwelling Older Adults: Findings from Korean Frailty and Aging Cohort Study.
Prevalence of Physical Frailty and Its Multidimensional Risk Factors in Korean Community-Dwelling Older Adults: Findings from Korean Frailty and Aging Cohort Study.
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DOI：
10.3390/ijerph17217883
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发表时间：
2020-10-27
影响因子：
--
通讯作者：
Won CW
中科院分区：
文献类型：
--
作者：
Jung H;Kim M;Lee Y;Won CW
脆弱被定义为一种对压力源的脆弱性增加的状态，它预测了老年人口的残疾和死亡率。本研究旨在调查韩国社区居住老年人中与虚弱相关的标准化患病率和多维风险因素。我们分析了2907名年龄在70-84岁（平均年龄75.8 ± 3.9岁，57.8%为女性）的韩国虚弱和老龄化队列研究的基线数据。Fried虚弱表型用于定义虚弱。分析的数据包括社会人口统计学、身体、身体功能、生物学、生活方式、健康状况、医疗状况、心理和社会领域。根据韩国人口和住房普查，使用国家标准人口构成比对数据进行标准化。虚弱和虚弱前期的标准化患病率分别为7.9%（95%置信区间（CI）6.8-8.9%）和47.0%（95% CI，45.1-48.8%）。以下14个风险因素与虚弱显著相关：有营养不良、肌肉减少症、严重活动受限、社会资本差、农村居民、抑郁症状、自我感觉健康差、多种药物、高敏C反应蛋白升高、糖化血红蛋白升高、25-羟基维生素D水平低、起床和行动时间较长的风险，和较低的短体力活动成套测验评分（p < 0.05）。身体营养、心理、社会人口学和医学因素与虚弱密切相关。
Frailty is defined as a state of increased vulnerability to stressors, and it predicts disability and mortality in the older population. This study aimed to investigate the standardized prevalence and multidimensional risk factors associated with frailty among Korean community-dwelling older adults. We analyzed the baseline data of 2907 adults aged 70–84 years (mean age 75.8 ± 3.9 years, 57.8% women) in the Korean Frailty and Aging Cohort Study. The Fried frailty phenotype was used to define frailty. Analyzed data included sociodemographic, physical, physical function, biological, lifestyle, health condition, medical condition, psychological, and social domains. Data were standardized using the national standard population composition ratio based on the Korean Population and Housing Census. The standardized prevalence of frailty and prefrailty was 7.9% (95% confidence interval (CI) 6.8–8.9%) and 47.0% (95% CI, 45.1–48.8%), respectively. The following 14 risk factors were significantly associated with frailty: at risk of malnutrition, sarcopenia, severe mobility limitation, poor social capital, rural dwellers, depressive symptoms, poor self-perceived health, polypharmacy, elevated high-sensitivity C-reactive protein, elevated glycosylated hemoglobin, low 25-hydroxy vitamin D level, longer Timed Up and Go, and low Short Physical Performance Battery score (p < 0.05). Physiconutritional, psychological, sociodemographic, and medical factors are strongly associated with frailty.
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