Chronotype in Patients With Immune-Mediated Inflammatory Disease: A Systematic Review.
Chronotype in Patients With Immune-Mediated Inflammatory Disease: A Systematic Review.
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免疫介导的炎症性疾病患者的表型：系统评价。
DOI：
10.1177/07487304221131114
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发表时间：
2023-03
影响因子：
3.5
通讯作者：
McLaughlin, John T.
中科院分区：
文献类型：
--
作者：
Butler, Thomas D.;Ali, Aala Mohammed;Gibbs, Julie E.;McLaughlin, John T.
免疫介导的炎症性疾病(IMID)，如类风湿性关节炎、炎症性肠病和哮喘，具有共同的病理生理途径，其特征是慢性炎症和随后的组织损伤，累及多个身体部位。昼夜节律是24小时的身体周期，它根据一天中的不同时间调节免疫活动并控制免疫反应的大小。时型是一个人从早晨到晚上的个体昼夜节律偏好，众所周知，这会影响心脏新陈代谢疾病和精神健康疾病的风险。我们系统地回顾文献以评估基于问卷的时型与IMID患者的关系。对MEDLINE和Embase的全面搜索确定了12项符合纳入标准的研究，这些研究在7个国家进行，涵盖4个IMID，包括15,625名IMID患者和410,783名健康对照。结果表明，较晚的时型可能是IMIDs患者生活质量较差和症状负担增加的危险因素。此外，时型可能是IMID发病的危险因素，但这种影响的方向和大小在不同的IMID中并不一致。时型评估有助于IMIDs患者的风险分层。跨学科合作，了解昼夜节律和时型在驱动常见炎症途径中的作用，可能有助于改善IMID患者的预后。
Immune-mediated inflammatory diseases (IMIDs) such as rheumatoid arthritis, inflammatory bowel disease, and asthma share common pathophysiological pathways characterized by chronic inflammation and subsequent tissue damage involving multiple body sites. Circadian rhythms are 24-h body cycles that regulate immune activity and control the magnitude of immune response based on time of day. Chronotype is a person’s individual circadian phase preference, ranging from morningness to eveningness, which is known to influence the risk of cardiometabolic and mental health disease. We systematically reviewed the literature to assess the association of questionnaire-based chronotype and patients with IMID. A comprehensive search of MEDLINE and Embase identified 12 studies meeting the inclusion criteria, conducted in 7 countries and covering 4 IMIDs to include 15,625 IMID patients and 410,783 healthy controls. Results showed that later chronotype may be a risk factor for worse quality of life and increased symptom burden in patients with IMIDs. In addition, chronotype may be a risk factor for IMID incidence, but the direction and magnitude of this effect were not consistent across individual IMIDs. Chronotype assessment could contribute to risk stratification in patients with IMIDs. Cross-disciplinary collaboration to understand the role of circadian rhythms and chronotype in driving common inflammatory pathways could help to improve outcomes for patients with IMIDs.
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影响因子：
4.9
作者：
Gibbs JE;Ray DW
通讯作者：
Ray DW
DOI：
10.1073/pnas.1619320114
发表时间：
2017-05-16
影响因子：
11.1
作者：
Anafi, Ron C.;Francey, Lauren J.;Kim, Junhyong
通讯作者：
Kim, Junhyong
影响因子：
10
作者：
Maidstone R;Anderson SG;Ray DW;Rutter MK;Durrington HJ;Blaikley JF
通讯作者：
Blaikley JF
影响因子：
4.5
作者：
Herzog R;Álvarez-Pasquin MJ;Díaz C;Del Barrio JL;Estrada JM;Gil Á
通讯作者：
Gil Á
DOI：
10.5935/1984-0063.20180017
发表时间：
2018-03
期刊：
Sleep science (Sao Paulo, Brazil)
影响因子：
--
作者：
Basnet S;Merikanto I;Lahti T;Männistö S;Laatikainen T;Vartiainen E;Partonen T
通讯作者：
Partonen T