Label-free real-time imaging of myelination in the Xenopus laevis tadpole by in vivo stimulated Raman scattering microscopy
Label-free real-time imaging of myelination in the Xenopus laevis tadpole by in vivo stimulated Raman scattering microscopy
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通过体内受激拉曼散射显微镜对非洲爪蟾蝌蚪髓鞘形成进行无标记实时成像
DOI:
10.1117/1.jbo.19.8.086005
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发表时间:
2014-08
影响因子:
3.5
通讯作者:
Hu, Bing
中科院分区:
文献类型:
--
作者:
Zhang, Delong;Slipchenko, Mikhail N.;Cheng, Ji-Xin;Hu, Bing
Abstract. The myelin sheath plays an important role as the axon in the functioning of the neural system, and myelin degradation is a hallmark pathology of multiple sclerosis and spinal cord injury. Electron microscopy, fluorescent microscopy, and magnetic resonance imaging are three major techniques used for myelin visualization. However, microscopic observation of myelin in living organisms remains a challenge. Using a newly developed stimulated Raman scattering microscopy approach, we report noninvasive, label-free, real-time in vivo imaging of myelination by a single-Schwann cell, maturation of a single node of Ranvier, and myelin degradation in the transparent body of the Xenopus laevis tadpole.
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DOI:
10.1117/12.2005504
发表时间:
2013-03
期刊:
--
影响因子:
--
作者:
K. Poon;C. Brideau;Wulin Teo;G. Schenk;Roel Klaver;A. Klauser;J. Kawasoe;J. Geurts;P. Stys
通讯作者:
K. Poon;C. Brideau;Wulin Teo;G. Schenk;Roel Klaver;A. Klauser;J. Kawasoe;J. Geurts;P. Stys
影响因子:
--
作者:
A. Goes;Christine D. Dijkstra
通讯作者:
A. Goes;Christine D. Dijkstra
影响因子:
--
作者:
Matthew L. Tomlinson;Adam E. Hendry;G. Wheeler
通讯作者:
Matthew L. Tomlinson;Adam E. Hendry;G. Wheeler
DOI:
10.1083/jcb.34.2.555
发表时间:
1967-08
期刊:
The Journal of cell biology
影响因子:
--
作者:
Hirano A;Dembitzer HM
通讯作者:
Dembitzer HM
影响因子:
--
作者:
Richard Crane;J. Ruderman
通讯作者:
Richard Crane;J. Ruderman