Smell and taste changes are early indicators of the COVID-19 pandemic and political decision effectiveness.

Smell and taste changes are early indicators of the COVID-19 pandemic and political decision effectiveness.
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气味和品味变化是19009年大流行和政治决策有效性的早期指标。

DOI:
10.1038/s41467-020-18963-y
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发表时间:
2020-10-14
影响因子:
16.6
通讯作者:
Bensafi M
Bensafi M
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Pierron D;Pereda-Loth V;Mantel M;Moranges M;Bignon E;Alva O;Kabous J;Heiske M;Pacalon J;David R;Dinnella C;Spinelli S;Monteleone E;Farruggia MC;Cooper KW;Sell EA;Thomas-Danguin T;Bakke AJ;Parma V;Hayes JE;Letellier T;Ferdenzi C;Golebiowski J;Bensafi M

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为应对COVID-19疫情,多国政府已采取严厉措施以避免重症监护病房人满为患。准确衡量疾病传播对重新开放战略至关重要。在这里,我们表明,自我报告的嗅觉/味觉变化与医院超负荷更密切相关,并且是SARS-CoV-2感染传播的早期标志物,而不是目前的政府指标。我们还报告说,早在实施封锁后5天,新出现的气味/味道变化的自我报告就有所减少。跨国比较表明,采取最严格封锁措施的国家在封锁后气味/味道变化的新报告下降速度快于采取较不严格封锁措施的国家。我们建议,普通人群中突然嗅觉和味觉变化的发生率增加可作为COVID-19在人群中传播的指标。对COVID-19的症状监测有助于确定传播增加的地区。在这里,作者表明,在人群水平上测量的嗅觉和味觉变化的报告增加与COVID-19相关的住院人数增加有关。
In response to the COVID-19 pandemic, many governments have taken drastic measures to avoid an overflow of intensive care units. Accurate metrics of disease spread are critical for the reopening strategies. Here, we show that self-reports of smell/taste changes are more closely associated with hospital overload and are earlier markers of the spread of infection of SARS-CoV-2 than current governmental indicators. We also report a decrease in self-reports of new onset smell/taste changes as early as 5 days after lockdown enforcement. Cross-country comparisons demonstrate that countries that adopted the most stringent lockdown measures had faster declines in new reports of smell/taste changes following lockdown than a country that adopted less stringent lockdown measures. We propose that an increase in the incidence of sudden smell and taste change in the general population may be used as an indicator of COVID-19 spread in the population. Syndromic surveillance for COVID-19 could help to identify areas with increasing transmission. Here, the authors show that increased reports of changes in smell and taste measured at the population level are correlated with the increased COVID-19-related hospital admissions.
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